SynthesisFrontiers in medicine2026
Stroke after lung transplantation: a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Stroke represents a significant but understudied complication following lung transplantation. No systematic review has synthesized the evidence on post-transplant stroke incidence and outcomes. This study aimed to determine the pooled incidence of stroke after lung transplantation, explore sources of heterogeneity, and synthesize evidence on mortality impact and risk factors. Methods: We searched PubMed, Embase, Cochrane Library, and Web of Science from inception to December 2025. Studies reporting stroke incidence in adult lung transplant recipients with extractable numerator and denominator data were included. Random-effects meta-analysis was performed for incidence pooling; mortality and risk factor data were synthesized narratively. Results: Seventeen studies (33,175 patients) were included. The pooled stroke incidence was 3.58% (95% CI: 2.86%-4.48%), with substantial heterogeneity (I Conclusion: Stroke affects approximately 1 in 28 lung transplant recipients and is associated with 3-fold increased mortality. Standardized definitions and prospective studies are needed to address gaps in risk stratification and prevention. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=1236324, identifier [CRD420251236324].
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.