Evidence map›Paper›PMID 41987778›Full record

ArticleFrontiers in medicine2026

Machine-learning for age-related macular degeneration using multimodal fundus data.

Mengke Li, Aiping Gu, Hongyang Li, Yanying Li, Renlong Liang, Ting Su, Yi Wu

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengke Li *Department of Ophthalmology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, China.
Aiping Gu *Department of Ophthalmology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, China.
Hongyang LiDepartment of Ophthalmology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, China.
Yanying LiDepartment of Ophthalmology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, China.
Renlong LiangDepartment of Ophthalmology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, China.
Ting SuDepartment of Ophthalmology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, China.
Yi WuDepartment of Ophthalmology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To develop an integrated model that combines multimodal fundus image features for accurately predicting the individualized risk of progression from early to late stages of age-related macular degeneration (AMD). Methods: A retrospective analysis was conducted on the data of 324 patients with AMD. The patients were randomly divided into a training set ( Results: There were no significant differences in the baseline characteristics between the training set and the validation set patients ( Conclusion: In this study, an AMD progression prediction model based on multimodal fundus images was successfully developed, which can effectively identify patients at high risk of progression and provide a new paradigm for clinical individualized precision medicine.

Indexed as

age-related macular degenerationdisease progressionmachine learningmultimodal imagingprediction modelrandom forest

Identifiers

PMID41987778
PMCPMC13076296

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.