Evidence map›Paper›PMID 41987328›Full record

ArticleJournal of pharmaceutical health care and sciences2026

A comparative study of the effectiveness of virtual reality-based and text-based training in sterile preparation: pilot trial of early-stage clinical VR study.

Satoru Esumi, Sari Nakagawa, Mai Ikemura, Yui Takezawa, Rika Ebara, Miho Harada, Akitoshi Tatsumi, Akiko Kanmachi, Yasuhiko Hashimoto, Mariko Takeda-Morishita

Abstract read
In one paragraph

Article in Journal of pharmaceutical health care and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Satoru EsumiFaculty of Pharmaceutical Sciences, Kobegakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, Japan.
Sari Nakagawa *Faculty of Pharmaceutical Sciences, Kobegakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, Japan. nakagawa@pharm.kobegakuin.ac.jp.
Mai IkemuraFaculty of Pharmaceutical Sciences, Kobegakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, Japan.
Yui TakezawaFaculty of Pharmaceutical Sciences, Kobegakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, Japan.
Rika EbaraFaculty of Pharmaceutical Sciences, Kobegakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, Japan.
Miho HaradaFaculty of Pharmaceutical Sciences, Kobegakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, Japan.
Akitoshi TatsumiFaculty of Pharmaceutical Sciences, Kobegakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, Japan.
Akiko KanmachiFaculty of Pharmaceutical Sciences, Kobegakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, Japan.
Yasuhiko Hashimoto *Faculty of Pharmaceutical Sciences, Kobegakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, Japan.
Mariko Takeda-Morishita *Faculty of Pharmaceutical Sciences, Kobegakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, Japan. mmtakeda@pharm.kobegakuin.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study is a pilot study evaluating the effectiveness of virtual reality (VR) applications in retraining sterile preparation techniques for injectable medications. Specifically, it focused on comparing VR-based learning with conventional text-based learning and objectively assessing students’ acquisition of practical skills using standardized evaluation criteria.

methodsSeventeen pharmacy students voluntarily participated in the study and were divided into two groups: one using a VR application for learning and the other using text-based materials. Immediately after training with their respective tools, students’ aseptic preparation skills were assessed using standardized criteria (including 29 individual evaluation checkpoints) and a 5-point overall rating scale.

resultsStudents who used the VR application completed tasks in a shorter time and scored higher on evaluation criteria such as operational smoothness and drug dissolution within vials. Additionally, multiple assessment items, including “Fill the aseptic smoothly and evenly, without stopping in the middle of the process,” were strongly correlated with the overall practical performance ratings of the VR group.

conclusionsThe introduction of VR applications for aseptic preparation training, which involves complex procedures, suggests that VR-based learning may be more effective than traditional text-based methods in helping students understand procedural workflows and improve operational fluency. These findings indicate that VR technology may serve as a useful educational tool in practical pharmacy training. Further studies with larger sample sizes are needed to confirm these findings.

trial registrationNot applicable

Indexed as

Pharmacy studentsPractical trainingSterile preparationVirtual reality

Identifiers

PMID41987328
PMCPMC13196225

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.