Evidence map›Paper›PMID 41987175›Full record

ArticleJournal of nanobiotechnology2026

Leveraging piezo-augmented copper-induced bacterial death of sub-1 nm CuO-SrTiO

Xueqing Wang, Kai Li, Wenyan Xu, Danyang Wang, Ying Wang, Junkun Feng, Yi Chen, Xiaoyi Liu, Zishan Xu, Xiaojia Liu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xueqing WangDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China.
Kai LiDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China. Kai.li@sdu.edu.cn.
Wenyan XuDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China.
Danyang WangDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China.
Ying WangDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China.
Junkun FengDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China.
Yi ChenDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China.
Xiaoyi LiuDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China.
Zishan XuDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China.
Xiaojia LiuDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China.
Shaohua GeDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China.
Hong LiuState Key Laboratory of Crystal Materials, Shandong University, Jinan, 250100, Shandong, China.
Jianhua LiDepartment of Biomaterials, School and Hospital of Stomatology, Shandong University & Shandong Key Laboratory of Oral Diseases & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Cheeloo College of Medicine, Jinan, 250012, China. jianhua.li@sdu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteomyelitis is a refractory bacterial infection of bone, presenting significant clinical management challenges due to its limited therapeutic outcome. Here, we developed heterojunction-structured sub-1 nm copper oxide-decorated strontium titanate nanosheets (Cu-STO NSs), which integrate piezocatalytic reactive oxygen species (ROS) generation with augmented copper-induced bacterial death for synergistic osteomyelitis treatment. Under ultrasound (US) irradiation, the oxygen vacancies and heterojunction structure of Cu-STO NSs facilitate the separation of piezo-generated electron-hole pairs while reducing energy barriers, thereby enhancing ROS generation. This process is augmented by the US-accelerated Cu

Indexed as

Anti-Bacterial AgentsCopperNanostructuresOsteomyelitisOxidesStrontiumTitaniumAnimalsOsteogenesisRatsRats, Sprague-DawleyReactive Oxygen SpeciesStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsCopperOxidesReactive Oxygen SpeciesStrontiumstrontium titanium oxideTitaniumAntibacterialCopper-induced metabolic toxicityHeterojunction structureOsteomyelitisPiezocatalysis

Identifiers

PMID41987175
PMCPMC13200504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.