ArticleBMC musculoskeletal disorders2026
Low cerebrospinal fluid pressure predisposes to postoperative epidural hematoma following lumbar decompression: a potentially modifiable physiological risk factor.
Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundPostoperative spinal epidural hematoma (SEH) is a serious complication of lumbar spinal surgery. While various risk factors have been reported, the role of cerebrospinal fluid (CSF) pressure in SEH development remains unclear. This study aimed to investigate the association between preoperative CSF pressure and postoperative SEH, and to explore potentially modifiable physiological factors.
methodsA total of 94 patients undergoing lumbar decompression surgery were retrospectively reviewed. Preoperative CSF pressure was measured via lumbar puncture in the lateral position before surgery. Patients were categorized into hematoma and no-hematoma groups based on postoperative magnetic resonance imaging findings. Clinical and surgical variables were compared between groups, and multivariable logistic regression analysis was performed to identify independent risk factors for SEH.
resultsPostoperative epidural hematoma with significant dural sac compression was observed in 30.8% of patients. Multivariable logistic regression analysis revealed that lower CSF pressure (adjusted OR = 0.87 per 10 mmH2O increase; 95% CI: [0.74–0.98], P = 0.028) and the number of decompressed levels (adjusted OR = 1.94; 95% CI: [1.15–3.47], P = 0.017) were independently associated with SEH development. Post hoc power analysis for CSF pressure yielded sufficient power of 0.81.
conclusionsLow preoperative CSF pressure was independently associated with postoperative SEH and may represent a potentially modifiable physiological factor. Perioperative strategies aimed at maintaining adequate CSF pressure may help reduce the risk of postoperative epidural hematoma, although their clinical effectiveness requires confirmation in prospective studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.