Evidence map›Paper›PMID 41987109›Full record

ArticleBMC pregnancy and childbirth2026

Knowledge, attitudes, practices, and future intentions to use intermittent preventive treatment with sulfadoxine-pyrimethamine among pregnant women in southern Ghana.

Matilda Aberese-Ako, Wisdom Ebelin, Pascal Magnussen, Kingsford Norshie, Desmond Klu, Mustapha Immurana, Gifty D Ampofo, Harry Tagbor

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matilda Aberese-AkoInstitute of Health Research, University of Health and Allied Sciences, PMB 31, Ho, Volta Region, Ghana. maberese-ako@uhas.edu.gh.
Wisdom EbelinEvangelical Presbyterian Health Services, Evangelical Presbyterian Headquarters, Ho, Volta Region, Ghana.
Pascal MagnussenDept. of Immunology and Microbiology, Centre for translational Medicine and Parasitology, University of Copenhagen, Copenhagen, Denmark.
Kingsford NorshieInstitute of Health Research, University of Health and Allied Sciences, PMB 31, Ho, Volta Region, Ghana.
Desmond KluInstitute of Health Research, University of Health and Allied Sciences, PMB 31, Ho, Volta Region, Ghana.
Mustapha ImmuranaInstitute of Health Research, University of Health and Allied Sciences, PMB 31, Ho, Volta Region, Ghana.
Gifty D AmpofoSchool of Medicine, University of Health and Allied Sciences, Ho, Volta Region, Ghana.
Harry TagborSchool of Medicine, University of Health and Allied Sciences, Ho, Volta Region, Ghana.

Funding

Wellcome Trust WT: 107741/A/15/Z
6 · The paper itself

Abstract

introductionMalaria in pregnancy is a significant public health concern in sub-Saharan Africa, affecting an estimated 32 million pregnant women annually. One of WHO’s recommendations for malaria prevention is the use of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP). However, reports indicate that less than 100% of women in Ghana access IPTp service. This study explored knowledge, attitudes, uptake, and future intentions to take IPTp-SP among pregnant women in southern Ghana. METHODOLOGY: An ethnographic study design was used. Data was collected from April 20,218 to March 2019 using in-depth interviews, conversations, and non-participant observations, among pregnant women, health workers, managers, and a cross-section of community members. The interviews were recorded digitally, transcribed, and uploaded together with the transcribed conversations and observation notes into NVivo Version 11 for triangulation, coding, and thematic analysis. All ethical procedures were followed.

resultsSix major themes were identified: The context of SP administration as observed at the ANC, Post-SP advice and counseling by health providers, Knowledge of the benefits of intermittent preventive therapy in pregnancy, Frequency of SP uptake and Knowledge of recommended dosing, experience in taking in SP, and intentions of future uptake of SP. The findings show that SP uptake was well integrated into routine antenatal care and delivered through a structured, provider-led process under direct observation. Mandatory water intake and advice to eat heavy meals were common practices. Counselling on SP varied across clients and was generally limited after administration, particularly regarding side effects. Most participants received three or more SP doses in line with national guidelines and demonstrated strong trust in healthcare providers. However, knowledge of correct dosage and timing was limited, with misconceptions evident. Despite experiencing discomfort such as nausea and dizziness, most women continued SP use due to perceived maternal and fetal benefits.

conclusionStrengthening communication between healthcare providers and pregnant women regarding dosing schedules, potential side effects, and follow-up doses could improve adherence and optimize the effectiveness of malaria prevention strategies.

Indexed as

AntimalarialsHealth Knowledge, Attitudes, PracticeMalariaPatient Acceptance of Health CarePregnancy Complications, ParasiticPregnant PeoplePyrimethamineSulfadoxineAdultCross-Sectional StudiesDrug CombinationsFemaleGhanaHumansIntentionPregnancyAntimalarialsDrug Combinationsfanasil, pyrimethamine drug combinationPyrimethamineSulfadoxineAntenatal careAttitudesGhanaHealth belief theoryHealthcare providersIPTp-SPKnowledgeMalariaPracticesPregnant womenQualitative study

Identifiers

PMID41987109
PMCPMC13191985

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.