Evidence map›Paper›PMID 41987086›Full record

Trial reportBMC musculoskeletal disorders2026

Combined mode-kinetic chain exercise with and without core stability exercises on patients with knee osteoarthritis.

Maryam Maqsood, Jannat Sohail, Syeda Aiman Batool

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06377813 (Effect of Combined Mode-Kinetic Chain Exercise With and Without Core Stability Exercises on Pain, Range of Motion, Quality of Life on Patients With Knee Osteoarthritis), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06377813 nacompletednot on this map

Effect of Combined Mode-Kinetic Chain Exercise With and Without Core Stability Exercises on Pain, Range of Motion, Quality of Life on Patients With Knee Osteoarthritis

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2024Enrolled48ConditionsKnee OsteoarthritisArmsMode-Kinetic Chain Exercise With Core Stability Exercises, Mode-Kinetic Chain Exercise
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maryam MaqsoodFaculty of Allied Health Sciences, Riphah International University, Islamabad, Pakistan.
Jannat SohailGovernment College University, Faisalabad, Faisalabad, Pakistan.
Syeda Aiman BatoolFaculty of Allied Health Sciences, University Institute of Physical Therapy, University of Lahore, Lahore, Pakistan. aiman.batool@uipt.uol.edu.pk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmong adult population, the osteoarthritis (OA) of knee is the major issue that can lead to pain, functional limitations, and reduced quality of life. Exercise therapy is a core component of management, yet the added value of core stability training in conjunction with kinetic chain exercises remains underexplored.

objectiveTo determine the effects of combined mode kinetic chain exercise with and without core stability training on pain, range of motion and quality of life in patients with knee OA.

methodsA total of 48 patients with osteoarthritis in their knees were the subjects of a randomized controlled experiment at PSRD Hospital in Lahore were randomly allocated to either Group B (kinetic chain exercise only) or Group A (kinetic chain exercise with core stability training) with 24 participants each. For 12 weeks, interventions were carried out three times a week. Quality of life (KOOS), knee range of motion (goniometry), and pain (NPRS) were evaluated at baseline, six weeks, and twelve weeks.

resultsGroup A and B both groups showed significant improvements in NPRS, ROM, and KOOS scores over time (p < 0.05). At 12 weeks, Group A demonstrated a greater reduction in pain compared to Group B (p = 0.002). Flexion ROM improved by 19.6° ± 3.2° in Group A versus 12.4° ± 2.9° in Group B (p < 0.001). KOOS total score increased by 34.8 ± 5.6 in Group A and 25.7 ± 5.1 in Group B (p < 0.001).

conclusionIncorporating core stability exercises into a kinetic chain exercise program yields superior improvements in pain reduction, knee range of motion and quality of life in knee osteoarthritis patients compared to kinetic chain exercises alone.

trial registrationThe study was registered at Clinical trial.gov and was submitted on 2024–04-18. Trial Registry number was NCT06377813.

Indexed as

Exercise TherapyKnee JointOsteoarthritis, KneeAgedFemaleHumansMaleMiddle AgedPain MeasurementQuality of LifeRange of Motion, ArticularTreatment OutcomeCore StabilityExercise TherapyKneeOsteoarthritisPainQuality of LifeRange of Motion

Identifiers

PMID41987086
PMCPMC13200492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.