ArticleBMC genomics2026
Integrative transcriptomic and metabolomic analysis reveals key genes and regulatory networks underlying seed germination in Polygonatum sibiricum.
Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Metabolo-Transcriptomic Analysis Reveals the Mechanisms Underlying Seed Dormancy Release inInternational journal of molecular sciences · 2026Article
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10 authors.
Funding
Abstract
backgroundPolygonatum sibiricum Red. (P. sibiricum) seeds exhibit strong dormancy, which prolongs germination period, reduces germination rate, and thus hinders its production. Research on breaking seed dormancy via optimized sand storage and clarifying germination-related mechanisms is insufficient. This study focused on optimizing sand storage conditions of P. sibiricum seeds and analyzing their biological traits, enzyme gene expressions, and metabolic changes to elucidate germination kinetics.
resultsThe predicted optimal conditions (GA3 130.497 mg/L, 4.90 °C, 1:1 sand: Huangjiang slag) gave a theoretical germination rate of 89.65% ± 0.31%; validation experiments achieved 89.31% ± 0.34%, confirming robustness. High abscisic acid (ABA) content was detected during dormancy; GA3, jasmonic acid (JA) increased during seed coat penetration, with indole-3-acetic acid (IAA) rising simultaneously. RNA sequencing (RNA-seq) identified 1,710 Differentially expressed genes (DEGs) involved in cell wall modification, endosperm degradation, phytohormone synthesis/signaling, etc. Liquid Chromatography-Mass Spectrometry (LC-MS) confirmed transcriptome results, highlighting beta-1, 2-Mannotriose, Isocitric acid, dAMP, AMP, and Methyl jasmonate as germination-related metabolites. Plant secondary metabolism, amino acid synthesis, and carbohydrate metabolism pathways were enriched during germination.
conclusionThis study determined GA3 concentration, temperature, and sand-slag ratio as key factors for P. sibiricum seed germination, providing optimal conditions with 89.31% ± 0.34% germination rate. It revealed a synergistic mechanism: ABA maintains dormancy, while GA3/JA/IAA promote germination; 1,710 DEGs and key metabolites regulate germination via core pathways. These findings support P. sibiricum seedling cultivation and industrial development.
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