Evidence map›Paper›PMID 41986723›Full record

ArticleNature2026

A spatial atlas of the healthy human liver from live donors.

Oran Yakubovsky, Keren Bahar Halpern, Sapir Shir, Roy Novoselsky, Amichay Afriat, Adi Egozi, Tal Barkai, Yotam Harnik, Rouven Hoefflin, Yael Korem Kohanim and 14 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Targeting macrophages in liver fibrosis.Frontiers in immunology · 2026
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Oran YakubovskyDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-8849-6615
Keren Bahar HalpernDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0001-6505-733X
Sapir ShirDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0009-0004-5514-6047
Roy NovoselskyDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-4464-0179
Amichay AfriatLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0002-5067-1887
Adi EgoziDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Tal BarkaiDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0003-1323-8117
Yotam HarnikDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0001-5099-3328
Rouven HoefflinDepartment of Internal Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-5197-453X
Yael Korem KohanimDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Ofra GolaniDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-9793-236X
Inna GoliandDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Yoseph AddadiDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0001-9827-0436
Merav KedmiDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Hadas Keren-ShaulDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Liat Fellus-AlyagorDepartment of Veterinary Resources, The Weizmann Institute of Science, Rehovot, Israel.
Lena PrichislovDepartment of Veterinary Resources, The Weizmann Institute of Science, Rehovot, Israel.
Dana HirschDepartment of Veterinary Resources, The Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-8575-0964
Chen MayerGray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Ron PeryDepartment of General Surgery and Transplantation, Sheba Medical Center, Ramat Gan, Israel.
Niv PencovichDepartment of General Surgery and Transplantation, Sheba Medical Center, Ramat Gan, Israel.
Timucin TanerDepartment of Surgery, Mayo Clinic, Rochester, MN, USA.
Ido NachmanyDepartment of General Surgery and Transplantation, Sheba Medical Center, Ramat Gan, Israel.
Shalev ItzkovitzDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel. shalev.itzkovitz@weizmann.ac.il.ORCID http://orcid.org/0000-0003-0685-2522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reconstructing gene expression atlases for human tissues is challenging due to limited access to healthy samples from live individuals. Neurologically deceased donors often show ischaemic changes, and tissues near diseased regions may have altered gene expression

Indexed as

Atlases as TopicHealthLiverLiving DonorsAdultAnimalsFatty LiverFemaleHepatocytesHumansIn Situ Hybridization, FluorescenceMaleMiceMiddle AgedSingle-Cell Gene Expression AnalysisSpatial Transcriptomics

Identifiers

PMID41986723
PMCPMC13216088

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.