ArticleClinical neuroradiology2026
Incidence of Fish-mouthing and Wall Malapposition of Different Flow Diverters in the Treatment of Cerebral Aneurysms: Device-specific Findings in a Retrospective Single-center Analysis.
Article in Clinical neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFlow diverter (FD) braid stability is crucial for optimal wall apposition, thereby reducing the risk of device-related complications following intracranial aneurysm treatment. We compared wall apposition characteristics across different FD designs to evaluate inter-device differences.
methodsRetrospective single-center analysis of 104 patients with 127 aneurysms treated with 121 FD (35 Derivo Embolization Devices (DED; Acandis, Pforzheim, Germany), 50 p64 (Phenox Wallaby, Bochum, Germany), 24 p48 (Phenox), 11 Silk (Balt, Montmorency, France), and 1 Pipeline (Medtronic, Dublin, Ireland)) between February 2013 and June 2023. The analysis focused on fish-mouthing-like deformities (≥ 10% focal diameter reduction at device ends) and the need for mechanical wall apposition maneuvers, as well as aneurysm occlusion, thrombus-associated events, and neurological outcomes.
resultsFish-mouthing-like deformities occurred more frequently with DED (50.0%) than with other FD-types (27.2%; p = 0.021), mainly due to "pre"-fish-mouthing (31.3% vs. 14.8%; p = 0.047). Mechanical wall apposition maneuvers were more often required in DED cases (60.0% vs. 25.6%; p < 0.001), particularly for proximal malapposition. Aneurysm occlusion rates were comparable at final FU (84.2% vs. 88.6%; p = 0.563). Thrombus-associated events occurred more frequently with DED (29.4% vs. 11.3%; p = 0.008), though neurological outcomes did not differ significantly (6.0% vs. 2.6%; p = 0.148). Mean FU time was 26.0 ± 21.0 months.
conclusionDED required more frequent intraprocedural wall apposition maneuvers and showed higher rates of fish-mouthing-like deformities compared with other FD-types. However, long-term aneurysm occlusion and neurological outcomes were comparable. These findings suggest that while DED deployment may require greater technical expertise, its safety and efficacy should be further evaluated in larger, multicenter studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.