Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026
The effect of thunder-fire moxibustion on cancer-related fatigue in patients with Qi stagnation and blood stasis type colorectal cancer undergoing chemotherapy: a randomized controlled trial.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
7 authors.
Funding
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Abstract
objectiveThis study aimed to evaluate the efficacy of thunder‑fire moxibustion (TFM) for cancer‑related fatigue (CRF) in patients with Qi stagnation and blood stasis syndrome undergoing chemotherapy for colorectal cancer.
methodsIn this randomized controlled trial, 77 patients with colorectal cancer undergoing chemotherapy were randomly assigned to either a control group (conventional care) or an experimental group (conventional care plus thunder-fire moxibustion, TFM). Both groups received two treatment courses, with five intervention sessions per course. The primary outcome was the change in Revised Piper Fatigue Scale (RPFS) scores. Secondary outcomes included sleep quality assessed by the Pittsburgh Sleep Quality Index (PSQI), quality of life measured using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30), Traditional Chinese Medicine (TCM) syndrome scores, routine blood indicators, and inflammatory factor levels.Assessments were conducted before and after two intervention cycles and during a follow-up period.
results
conclusionThunder‑fire moxibustion may be an effective supportive intervention for reducing fatigue and improving sleep and quality of life in patients with colorectal cancer undergoing chemotherapy.
trial registrationThis study was registered on February 11, 2025, at the International Traditional Medicine Clinical Trial Registry (Registration Number: ITMCTR2025000305).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.