Evidence map›Paper›PMID 41985162›Full record

ArticleThe Plant journal : for cell and molecular biology2026

Loss of flavonol 3-O-glucosyltransferase activity confers soybean resistance to leaf-chewing insects.

P K Prabhakar, M A Ortega, B-K Ha, P R LaFayette, S A Harding, C J Tsai, B R Urbanowicz, H R Boerma, W A Parrott

Abstract read
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In one paragraph

Article in The Plant journal : for cell and molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

P K Prabhakar *Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, Georgia, 30602, USA.ORCID https://orcid.org/0000-0003-2450-5890
M A Ortega *Institute of Plant Breeding, Genetics, and Genomics, University of Georgia, 111 Riverbend Road, Athens, Georgia, 30602, USA.ORCID https://orcid.org/0000-0002-0447-9982
B-K HaCenter for Applied Genetic Technologies, University of Georgia, Athens, Georgia, 30602, USA.ORCID https://orcid.org/0000-0002-2295-365X
P R LaFayetteCenter for Applied Genetic Technologies, University of Georgia, Athens, Georgia, 30602, USA.ORCID https://orcid.org/0000-0002-9416-9952
S A HardingSchool of Forestry and Natural Resources, University of Georgia, Athens, Georgia, 30602, USA.ORCID https://orcid.org/0000-0001-5098-2370
C J TsaiSchool of Forestry and Natural Resources, University of Georgia, Athens, Georgia, 30602, USA.ORCID https://orcid.org/0000-0002-9282-7704
B R UrbanowiczComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, Georgia, 30602, USA.ORCID https://orcid.org/0000-0001-5247-4513
H R BoermaInstitute of Plant Breeding, Genetics, and Genomics, University of Georgia, 111 Riverbend Road, Athens, Georgia, 30602, USA.
W A ParrottInstitute of Plant Breeding, Genetics, and Genomics, University of Georgia, 111 Riverbend Road, Athens, Georgia, 30602, USA.ORCID https://orcid.org/0000-0001-7847-1134

Funding

Georgia Agricultural Commodity Commission for SoybeanNational Institute of Food and Agriculture 2112-67013-19456United Soybean Board 9236-0236U.S. Department of Energy (DOE) DE-SC0023223
6 · The paper itself

Abstract

Caterpillars and beetles are among the most economically damaging defoliating insects, and their economic damage is predicted to increase in the coming decades. Hence the use of genetically derived resistance to supplement other pest control strategies is warranted. In soybean (Glycine max (L.) Merr.), a major determinant for resistance is the quantitative trait locus, QTL-M. Glyma07g14530, the gene underlying QTL-M, encodes a feeding-inducible flavonol 3-O-glycosyltransferase (F3GlcT or UGT78D2) that glucosylates kaempferol, as well as quercetin, myricetin, and isorhamnetin. The resistant allele has a premature stop codon in it, thus preventing the glucosylation and sequestration of flavonols in the vacuole, leading to a concomitant accumulation of proanthocyanidins and manifestation of resistance. Expressing the dominant (susceptible) allele in resistant plants restores susceptibility, and silencing the susceptible allele results in resistance. The discovery and characterization of GmF3GlcT helps clarify the role of flavonoids in resistance to leaf-chewing insects and facilitates the development of insect-resistant cultivars that ultimately can lower production costs and reduce insecticide applications.

Indexed as

GlucosyltransferasesGlycine maxPlant ProteinsAnimalsFlavonolsPlant LeavesPlants, Genetically ModifiedQuantitative Trait Lociflavonol 3-O-glucosyltransferaseFlavonolsGlucosyltransferasesPlant Proteinsdefoliating insect resistanceflavonolsMexican bean beetle (Epilachna varivestis Mulsant)soybean (Glycine max (L.) Merr.)soybean looper (Chrysodeixis includens Walker)

Identifiers

PMID41985162
PMCPMC13082823

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.