Evidence map›Paper›PMID 41985113›Full record

ArticleJCO oncology practice2026

Translating Cancer Genetics Care: Digital Tools to Improve Cancer Genetics Risk Assessment for Patients With Limited English Proficiency.

Isabelle R Chandler, Melissa K Frey, Emily Webster, Muhammad Danyal Ahsan, Roxanna Haghighat, Benjamin Grant, Steve Lopez, Shifa Hossain, Xiaoyue Ma, Eloise Chapman-Davis and 4 more

Abstract read
In one paragraph

Article in JCO oncology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Isabelle R ChandlerDivision of Obstetrics and Gynecology, Division of Gynecologic Oncology, Weill Cornell Medicine, New York, NY.ORCID 0009-0000-0354-030X
Melissa K FreyDivision of Obstetrics and Gynecology, Division of Gynecologic Oncology, Weill Cornell Medicine, New York, NY.ORCID 0000-0002-6705-1211
Emily WebsterDivision of Obstetrics and Gynecology, Division of Gynecologic Oncology, Weill Cornell Medicine, New York, NY.ORCID 0000-0002-3208-4320
Muhammad Danyal AhsanGenetics and Personalized Cancer Prevention Program, Weill Cornell Medicine, New York, NY.ORCID 0000-0001-8633-8931
Roxanna HaghighatDepartment of Obstetrics and Gynecology, NewYork Presbyterian-Weill Cornell Medicine, New York, NY.ORCID 0000-0001-6615-9194
Benjamin GrantWeill Cornell Medical College, New York, NY.ORCID 0009-0008-4883-561X
Steve LopezDivision of Obstetrics and Gynecology, Division of Gynecologic Oncology, Weill Cornell Medicine, New York, NY.ORCID 0009-0008-7234-4669
Shifa HossainWeill Cornell Medical College, New York, NY.ORCID 0009-0008-4691-2757
Xiaoyue MaDivision of Biostatistics and Epidemiology, Weill Cornell Medicine, New York, NY.ORCID 0000-0002-8099-8979
Eloise Chapman-DavisDivision of Obstetrics and Gynecology, Division of Gynecologic Oncology, Weill Cornell Medicine, New York, NY.
Michelle PrimianoGenetics and Personalized Cancer Prevention Program, Weill Cornell Medicine, New York, NY.ORCID 0009-0007-9422-1451
David A FishmanDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, NewYork-Presbyterian Queens, New York, NY.
Lisa C DiamondMemorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-2175-6224
Ravi N SharafGenetics and Personalized Cancer Prevention Program, Weill Cornell Medicine, New York, NY.ORCID 0000-0002-6905-9823

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Implementing Universal Lynch Syndrome Screening across Multiple Healthcare Systems: Identifying Strategies to Facilitate and Maintain Programs in Different Organizational ContextsR01CA211723 · NCI · GEISINGER CLINIC · PI RAHM, ALANNA K · 2017 to 2021
$3.7M
Gene Dependent Cancer Risk and Optimal Cancer Prevention Strategies in Lynch SyndromeK07CA216326 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SHARAF, RAVI · 2018 to 2021
$675k
NCI NIH HHS K07 CA216326NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA211723
6 · The paper itself

Abstract

purposeThis study assessed the acceptability of a multilingual, digital cancer genetics risk assessment (CGRA) tool among patients with limited English proficiency at linguistically diverse, urban gynecology clinics. MATERIALS AND

methodsPatients presenting for gynecology appointments who spoke English, Spanish, or Chinese (Mandarin/Cantonese) were offered at check-in to complete a digital CGRA tool available in their preferred language. A convenience sample of 35 patients was selected per language group. The digital tool used patient-reported personal and family health histories to determine genetic testing eligibility based on National Comprehensive Cancer Network criteria. Primary outcomes were patient interest and completion of the digital tool across language groups. Patient interest in completing genetic testing following completion of the digital tool was not measured. Patient interest and completion of the digital tool were compared based on language, using chi-square test or Fisher's exact test. Multivariable logistic regression analysis was used to explore the effect of language, adjusting for other patient-related factors.

resultsOf the 105 patients offered the digital tool, 68 (64.8%) initiated the digital tool, among whom 51 (75.0%) completed it. The median age was 46.0 years (IQR, 37-58 years). No significant differences were found between English-speaking and Spanish-speaking patients (interest: 80.0%

conclusionThe digital CGRA tool was acceptable to 65% of patients. Spanish-speaking patients showed similar interest and completion rates as English speakers, whereas Chinese-speaking patients had lower interest and completion rates.

Identifiers

PMID41985113
PMCPMC13465891

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.