Evidence map›Paper›PMID 41984811›Full record

ArticlePloS one2026

Is early childhood education associated with better midlife cognition, especially for children facing socioeconomic marginalization?

Whitney Wells, Jillian Hebert, Chloe W Eng, Catherine dP Duarte, Anusha M Vable

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Whitney WellsDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0002-5142-9849
Jillian HebertSchool of Public Health, Washington University in St. Louis, St. Louis, Missouri, United States of America.ORCID https://orcid.org/0000-0003-4893-8287
Chloe W EngDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, United States of America.
Catherine dP DuarteDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, United States of America.
Anusha M VableSchool of Public Health, Washington University in St. Louis, St. Louis, Missouri, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEducation is a strong predictor of cognitive aging, but little work has evaluated the relationship between early childhood education (ECE) specifically and cognition in midlife and beyond.

methodsUsing data from the National Longitudinal Survey of Youth 1979 Cohort (n = 7,129), we examined the relationship between attending preschool, Head Start (federally-funded free ECE targeted for low-income families), or no ECE, and midlife global cognition. We defined midlife global cognition based on immediate and delayed word recall, serial 7 subtraction, and backwards counting. We used multivariable linear regression models to estimate overall associations and associations among groups more likely eligible for Head Start, and to evaluate heterogeneities by sex, race and ethnicity, and family socioeconomic status (SES).

resultsOverall, preschool, but not Head Start, was associated with better midlife cognition compared to no ECE in some models. Among families more likely eligible for Head Start, we found not only that preschool (β = 0.26; 95% CI: 0.01, 0.51) was associated with better midlife cognition, but also directionally positive evidence that Head Start (β = 0.09; 95% CI: -0.08, 0.27) was associated with better midlife cognition. Associations varied; Head Start was associated with higher midlife cognition for Black and Hispanic men and people with higher family SES marginalization compared to other groups.

conclusionsThis study provides initial evidence suggesting that early childhood education may be associated with better cognition more than 40 years later, especially for Black and Hispanic men and people who faced greater socioeconomic marginalization.

Indexed as

CognitionEarly Intervention, EducationalAdultChildChild, PreschoolFemaleHumansLongitudinal StudiesLow Socioeconomic StatusMaleMiddle AgedSocial ClassSocioeconomic Disparities in HealthSocioeconomic Factors

Identifiers

PMID41984811
PMCPMC13082659

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.