Evidence map›Paper›PMID 41984734›Full record

ArticleVirulence2026

Phosphorylation of a novel STK substrate SstP1 links SUF Fe-S cluster biogenesis to oxidative stress resistance and virulence in

Shuying Ren, Hang Yin, Yiming Wang, Ru Yan, Xiaoyu Jia, Zhiwei Li, Yuqing Li, Yutong Tian, Lianci Peng, Juan Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shuying RenJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.
Hang YinJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.
Yiming WangJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.
Ru YanJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.
Xiaoyu JiaJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.
Zhiwei LiJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.
Yuqing LiJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.
Yutong TianJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.
Lianci PengJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.ORCID 0000-0002-9005-3186
Juan LiJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.
Rendong FangJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing, China.ORCID 0000-0003-3094-5059

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron-sulfur (Fe-S) clusters are ancient prosthetic groups that are incorporated into apoproteins to generate fully functional Fe-S proteins, representing a conserved regulatory pathway in both Eukarya and Prokaryotes. In bacteria, the sulfur utilization factor (SUF) system mediates Fe-S cluster biosynthesis under stress conditions, thereby supporting essential metabolic processes to resist oxidative stress. In this study, we identify a novel substrate of serine/threonine kinase (STK), the protein with a DUF1831 domain (named as SstP1) in

Indexed as

Bacterial ProteinsIron-Sulfur ProteinsOxidative StressProtein Serine-Threonine KinasesStreptococcus suisAnimalsDisease Models, AnimalMicePhosphorylationStreptococcal InfectionsVirulenceBacterial ProteinsIron-Sulfur ProteinsProtein Serine-Threonine KinasesFe-S cluster biogenesisoxidative stress resistanceSTKStreptococcus suisvirulence

Identifiers

PMID41984734
PMCPMC13085941

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.