Evidence map›Paper›PMID 41984282›Full record

ReviewJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

Twiddler syndrome and Reel syndrome in patients with subcutaneous implantable cardioverter-defibrillator (S-ICD): a meta-summary of case reports.

Giovanni Domenico Ciriello, Diego Colonna, Anna Correra, Giovanni Papaccioli, Emanuele Romeo, Giuseppe Limongelli, Berardo Sarubbi

Abstract readCase ReportsReview
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In one paragraph

Review in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giovanni Domenico CirielloAdult Congenital Heart Disease Unit and Familial Arrhythmias Unit, Monaldi Hospital, Via Leonardo Bianchi, Naples, 80131, Italy. gdciriello@gmail.com.
Diego ColonnaAdult Congenital Heart Disease Unit and Familial Arrhythmias Unit, Monaldi Hospital, Via Leonardo Bianchi, Naples, 80131, Italy.
Anna CorreraAdult Congenital Heart Disease Unit and Familial Arrhythmias Unit, Monaldi Hospital, Via Leonardo Bianchi, Naples, 80131, Italy.
Giovanni PapaccioliAdult Congenital Heart Disease Unit and Familial Arrhythmias Unit, Monaldi Hospital, Via Leonardo Bianchi, Naples, 80131, Italy.
Emanuele RomeoAdult Congenital Heart Disease Unit and Familial Arrhythmias Unit, Monaldi Hospital, Via Leonardo Bianchi, Naples, 80131, Italy.
Giuseppe LimongelliInherited and Rare Cardiovascular Disease Clinic, University of Campania "Luigi Vanvitelli" - Monaldi Hospital, Naples, Italy.
Berardo SarubbiAdult Congenital Heart Disease Unit and Familial Arrhythmias Unit, Monaldi Hospital, Via Leonardo Bianchi, Naples, 80131, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTwiddler and Reel syndrome are mechanical complications of transvenous devices and are rarely reported in subcutaneous ICD (S-ICD) recipients.

methodsWe reviewed published cases and report Reel syndrome in a 15-year-old patient with an S-ICD, the youngest described.

resultsTen cases were identified. The most common clinical presentation was inappropriate shocks due to altered sensing vectors. Diagnosis was confirmed by device interrogation and chest radiography. Risk factors are similar to those observed in transvenous devices.

conclusionsTwiddler and Reel syndrome can occur in S-ICDs and should be considered in the differential diagnosis of inappropriate shocks or device malfunction.

Indexed as

Defibrillators, ImplantableForeign-Body MigrationAdolescentEquipment FailureHumansProsthesis FailureSyndromeInappropriate shockLead dislodgementReel syndromeSubcutaneous defibrillatorTwiddler syndrome

Identifiers

PMID41984282

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.