Evidence map›Paper›PMID 41984259›Full record

ArticleArchives of virology2026

Characterization and genomic analysis of a novel Vibrio harveyi Vibrio phage LRZ.

Zhengyu Yang, Hui Ge, Nan Chen, Yongrui Zhang, Huina Wei, Jinbo Hu, Chao Fan, Yilei Wang, Ziping Zhang

Abstract read
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In one paragraph

Article in Archives of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhengyu YangState Key Laboratory of Mariculture Breeding, Key Laboratory of Marine Biotechnology of Fujian Province, College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Hui GeKey Laboratory of Cultivation and High-Value Utilization of Marine Organisms in Fujian Province, Fisheries Research Institute of Fujian, Xiamen, 361013, China.
Nan ChenState Key Laboratory of Mariculture Breeding, Key Laboratory of Marine Biotechnology of Fujian Province, College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Yongrui ZhangState Key Laboratory of Mariculture Breeding, Key Laboratory of Marine Biotechnology of Fujian Province, College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Huina WeiState Key Laboratory of Mariculture Breeding, Key Laboratory of Marine Biotechnology of Fujian Province, College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Jinbo HuState Key Laboratory of Mariculture Breeding, Key Laboratory of Marine Biotechnology of Fujian Province, College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Chao FanState Key Laboratory of Mariculture Breeding, Key Laboratory of Marine Biotechnology of Fujian Province, College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Yilei WangState Key Laboratory of Mariculture Breeding, Key Laboratory of Healthy Mariculture for the East China Sea, Ministry of Agriculture and Rural Affairs, Fisheries College, Jimei University, Xiamen, 361021, China. ylwang@jmu.edu.cn.
Ziping ZhangState Key Laboratory of Mariculture Breeding, Key Laboratory of Marine Biotechnology of Fujian Province, College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China. zhangziping@hotmail.com.ORCID http://orcid.org/0000-0003-2802-1586

Funding

Independent Research Project of State Key Laboratory of Mariculture Breeding MBL251R18
6 · The paper itself

Abstract

Bacteriophages (phages), viruses that specifically infect and lyse their host bacteria, hold significant potential for application in the prevention of Vibrio infections and the treatment of vibriosis for aquaculture. In this study, a novel Vibrio harveyi phage, designated Vibrio Vibrio phage LRZ, was isolated from an abalone aquaculture farm in Lianjiang, Fujian Province. Its biological characteristics and complete genomic sequence were investigated. The results demonstrated that Vibrio phage LRZ exhibits robust tolerance to acidic/alkaline environments, as well as elevated temperatures. The phage exhibited a latent period of approximately 30 min and reached the plateau phase at approximately 190 min post-infection, with an estimated burst size of 134 plaque-forming units (PFU) per cell. Whole-genome sequencing using the Illumina platform revealed a genome length of 43,274 base pairs (bp) with a guanine-cytosine (GC) content of 39.45%. Annotation identified 51 open reading frames (ORFs), encoding proteins involved in phage structural assembly, host lysis, DNA replication, and metabolism. Bioinformatic predictions did not identify antibiotic resistance or virulence genes in the LRZ genome. BLAST comparative analysis indicated the highest similarity (75.47%) to Vibrio phage VPMS1, establishing Vibrio phage LRZ as a novel isolate of Vibrio phages. Phylogenetic analysis further confirmed its closest relationship to Vibrio phage VPMS1, placing them within the same genus in the class Caudoviricetes. Vibrio phage LRZ could serve as a valuable novel genomic resource for studying phage evolution and offers novel perspectives for the biocontrol of V. harveyi in aquaculture settings.

Indexed as

BacteriophagesGenome, ViralVibrioAnimalsAquacultureBase CompositionDNA, ViralGenomicsOpen Reading FramesPhylogenyWhole Genome SequencingDNA, Viral

Identifiers

PMID41984259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.