SynthesisLangenbeck's archives of surgery2026
Effect of enhanced recovery after surgery on the rehabilitation of patients undergoing laparoscopic pancreaticoduodenectomy: A meta-analysis.
Synthesis in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
objectiveto thoroughly assess how well patients having laparoscopic pancreaticoduodenectomy (LPD) respond to Enhanced Recovery After Surgery (ERAS) procedures.
methodsUp until March 2026, Chinese and English databases (China National Knowledge Infrastructure, Wanfang, VIP, PubMed, Embase, Cochrane, etc.) were searched for randomized controlled trials and cohort studies on the use of ERAS in LPD. Following screening, studies were subjected to data extraction and quality evaluation. RevMan 5.4 was used to conduct the meta-analysis. PROSPERO has this study registered (CRD No.: CRD420251115058).
resultsA total of 18 studies involving 1,672 patients were included. Results showed that implementing ERAS management during the perioperative period for LPD significantly shortened the time to early ambulation (MD = -0.88, 95% CI: -1.36 to -0.40), time to first flatus (MD = -0.97, 95% CI: -1.30 to -0.64), Time to drainage tube removal (MD = -2.25, 95% CI: -2.61 to -1.89), and postoperative hospital stay (MD = -3.67, 95% CI: -4.92 to -2.43). It also effectively reduced the overall complication rate (OR = 0.42, 95% CI: 0.32-0.55), and reduce the incidence of delayed gastric emptying (OR = 0.37, 95% CI: 0.21-0.66) and biliary fistula (OR = 0.30, 95% CI: 0.13-0.69). All differences were statistically significant (P < 0.05).
conclusionERAS use in LPD patients is safe and efficient throughout the perioperative phase, greatly accelerating recovery after surgery, lowering the risk of complications, and minimizing hospital stays.
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