Evidence map›Paper›PMID 41984095›Full record

ArticleArchives of toxicology2026

Aryl hydrocarbon receptor orchestrates transcriptomic, non-coding and splicing programs that drive human lung epithelial responses to vaporized cannabis in vitro.

Emily T Wilson, David H Eidelman, Carolyn J Baglole

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily T WilsonDepartment of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.
David H EidelmanCentre for Translational Biology (CTB), Research Institute of the McGill University Health Centre, Block E, 1001 Boul. Décarie, Montreal, QC, H4A 3J1, Canada.
Carolyn J BagloleDepartment of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada. carolyn.baglole@mcgill.ca.ORCID 0000-0002-3107-0437

Funding

CIHR 162273
6 · The paper itself

Abstract

Cannabis vaping is increasingly consumed as an alternative to cannabis smoke, yet its health consequences remain poorly defined. Vaporization may reduce the formation of combustion-related toxicants, but emerging data suggest that cannabis vaping still elicits deleterious effects in respiratory epithelial cells. While the actions of cannabis are commonly attributed to cannabinoid receptors, other molecular targets such as the aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, may play a role. In this study, we used wild-type (A549

Indexed as

Basic Helix-Loop-Helix ProteinsCannabisReceptors, Aryl HydrocarbonTranscriptomeA549 CellsCell ProliferationDronabinolEpithelial CellsHumansLungRNA, Long NoncodingRNA SplicingVolatilizationAHR protein, humanBasic Helix-Loop-Helix ProteinsDronabinolReceptors, Aryl HydrocarbonRNA, Long NoncodingAlternative splicingAryl hydrocarbon receptorCannabisCell cycleLncRNAProliferation

Identifiers

PMID41984095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.