Evidence map›Paper›PMID 41984076›Full record

ArticleeLife2026

A lipoprotein partner for the

Jim Horne, Elise Kaplan, Ben Jin, Kieran Abbott, Victor Flores, Emmanouela Petsolari, Jan Gradon, Yvette Ntsogo, Andrzej Harris, Dingquan Yu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jim Horne *Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0001-5260-2634
Elise Kaplan *Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0003-4985-1482
Ben JinDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0009-0006-3491-9404
Kieran AbbottDepartment of Genetics, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0009-0006-3369-5920
Victor FloresDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0003-4186-9151
Emmanouela PetsolariDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Jan GradonDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Yvette NtsogoDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Andrzej HarrisDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0003-4885-7401
Dingquan YuDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Ashraf ZarkanDepartment of Genetics, University of Cambridge, Cambridge, United Kingdom.
Ben F LuisiDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0003-1144-9877

Funding

European Research Council 742210Isaac Newton Trust 21.22(a)iiiRosetrees Trust JS16/TT12021\1School of the Biological Sciences, University of Cambridge Transition to IndependenceWellcome Trust 10.35802/222451
6 · The paper itself

Abstract

The outer membrane protein TolC from

Indexed as

Bacterial Outer Membrane ProteinsEscherichia coliEscherichia coli ProteinsLipoproteinsMembrane Transport ProteinsATP-Binding Cassette, Sub-Family C ProteinsATP-Binding Cassette TransportersCryoelectron MicroscopyProtein BindingAcrA protein, E coliAcrB protein, E coliATP-Binding Cassette, Sub-Family C ProteinsATP-Binding Cassette TransportersBacterial Outer Membrane ProteinsEscherichia coli ProteinsLipoproteinsMacA protein, E coliMembrane Transport ProteinstolC protein, E coliAcrABZ-TolCbiochemistrychemical biologyE. colilipoproteinMacAB-TolCmembrane protein assemblymolecular biophysicsmulti-drug efflux pumpstructural biology

Identifiers

PMID41984076
PMCPMC13082787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.