Evidence map›Paper›PMID 41983991›Full record

ArticleJournal of Alzheimer's disease : JAD2026

Management of dementia risk factors by memory clinic patients and professionals: Pilot study of the BreinZorg (BrainCare) online platform.

Lotte S Truin, Irene S Heger, Kay Deckers, Rani Knops, Tanya Palsma, Rianne A A de Heus, Jurgen A H R Claassen, Marjolein E de Vugt, Sebastian Köhler

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lotte S TruinAlzheimer Centre Limburg, Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.ORCID 0009-0002-4955-0153
Irene S HegerAlzheimer Centre Limburg, Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.
Kay DeckersAlzheimer Centre Limburg, Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-1339-2974
Rani KnopsAlzheimer Centre Limburg, Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.
Tanya PalsmaDepartment of Geriatric Medicine, Radboud Alzheimer Center, Radboud University Medical Center, Nijmegen, The Netherlands.
Rianne A A de HeusDepartment of Geriatric Medicine, Radboud Alzheimer Center, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0001-9676-001X
Jurgen A H R ClaassenDepartment of Geriatric Medicine, Radboud Alzheimer Center, Radboud University Medical Center, Nijmegen, The Netherlands.
Marjolein E de VugtAlzheimer Centre Limburg, Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.
Sebastian KöhlerAlzheimer Centre Limburg, Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.ORCID 0000-0002-2398-0609

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundBrain-healthy lifestyle changes could help reduce dementia risk in individuals with subjective cognitive decline (SCD) or mild cognitive impairment (MCI), but patients and clinicians in memory clinics often lack practical tools to support this.ObjectiveTo explore the acceptability and usability of BreinZorg (English: BrainCare) in a memory clinic setting. BreinZorg is a co-created prototype consisting of a self-management website and hardcopy conversation aid providing dementia risk reduction information.MethodsThe website includes a lifestyle assessment, personalized module recommendations, practical information on 16 modifiable dementia risk and protective factors (e.g., smoking, sleep) and a goal-setting feature. The hardcopy conversation aid briefly outlines these factors to support clinical risk reduction discussions. This study used semi-structured interviews based on the Program Participation Questionnaire and think-aloud sessions, which were analyzed through thematic content analysis. Participants were individuals with self-reported SCD or MCI (n = 19) and memory clinic professionals (n = 9), i.e., nurses/nurse practitioners, physicians/medical specialists and neuropsychologists.ResultsBreinZorg was generally considered useful, trustworthy, easy to use, and applicable in clinical contexts. The platform's accessible design, nonjudgmental tone, and personalization features were appreciated. Some participants with SCD or MCI, particularly those already interested in brain health, desired more in-depth information. A lack of follow-up on personal goals and misaligned module recommendations after the lifestyle assessment were identified as barriers to sustained engagement.ConclusionsMemory clinic patients and professionals evaluated BreinZorg as practical, useful, and acceptable for supporting dementia risk reduction in clinical care. Offering more detailed information, integrating tailored follow-up support, and enhancing personalization may strengthen long-term user engagement.

Indexed as

Cognitive DysfunctionDementiaHealth PersonnelInternetAgedAged, 80 and overFemaleHumansMaleMiddle AgedPilot ProjectsRisk FactorsRisk Reduction BehaviorSurveys and QuestionnairesAlzheimer's diseasemild cognitive impairmentpreventionrisk factorssubjective cognitive decline

Identifiers

PMID41983991
PMCPMC13219754

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.