Evidence map›Paper›PMID 41983816›Full record

ArticleCadernos de saude publica2026

[Drug safety: advances and challenges on the path to excellence at Brazilian hospitals].

Graça Rocha Pessoa, Lucilane Maria Sales da Silva, Jaira Gonçalves Trigueiro, Talina Carla da Silva

Abstract readEnglish Abstract
In one paragraph

Article in Cadernos de saude publica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Graça Rocha PessoaUniversidade do Estado do Rio Grande do Norte, Pau dos Ferros, Brasil.ORCID 0000-0002-5772-8540
Lucilane Maria Sales da SilvaUniversidade Estadual do Ceará, Fortaleza, Brasil.ORCID 0000-0002-3850-8753
Jaira Gonçalves TrigueiroUniversidade do Estado do Rio Grande do Norte, Pau dos Ferros, Brasil.ORCID 0000-0002-8597-4167
Talina Carla da SilvaInstituto de Ensino do Hospital do Coração, São Paulo, Brasil.ORCID 0000-0001-8859-1738

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim was to analyze changes in drug safety practices in Brazil from 2016 to 2023. A retrospective documental study was conducted based on reports from the Brazilian National Assessment of Patient Safety Practices. Data were collected from national Pareto graphs and analyzed in light of Pareto Theory, which states the most vital elements are responsible for 80% of problems. A total of 68% of Brazilian hospitals with ICU beds adhered to the evaluation of patient safety practices by 2023. Among 21 indicators, an average of 12 vital practices were identified as sources of noncompliance. The degree of compliance was greater in the structure domain compared to the process domain. Drug safety was among the most critical sources of noncompliance. A progressive improvement occurred between 2016 and 2019, with a reduction in noncompliance from 9% to 5.82%. Beginning in 2020, however, a tendency toward stagnation was found, with the percentage of noncompliance maintained at around 6% until 2023. The interruption in progress may be attributed to the COVID-19 pandemic, during which efforts and resources were diverted to help deal with the health crisis. The results enable an empirical understanding of advances and limitations with regards to adherence to drug safety practices at Brazilian hospitals, which contributes to strengthening knowledge on the current maturity of the safety culture in Brazil and the development of effective management strategies for the Brazilian Unified National Health System and drug safety.

Indexed as

Guideline AdherenceHospitalsPatient SafetyBrazilCOVID-19HumansRetrospective Studies

Identifiers

PMID41983816
PMCPMC13078777

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