Evidence map›Paper›PMID 41983805›Full record

ArticleRevista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria2026

Efficacy of a single-dose topical formulation combining Fipronil, Moxidectin and Praziquantel against natural infestations of Notoedres cati, Otodectes cynotis and Felicola subrostratus in cats.

Diefrey Ribeiro Campos, Eduardo Fellipe Melo Santos Soares, Breno Cayeiro Cruz, Gabriela Pereira Salça de Almeida, Gessica Ariane de Melo Cruz, Milenni Garcia Michels, Ferdinando Nielsen de Almeida, Igor Renan Honorato Gatto, Thais Ribeiro Correia, Fabio Barbour Scott

Abstract read
In one paragraph

Article in Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Diefrey Ribeiro CamposUniversidade Federal Rural Rio de Janeiro, Instituto de Medicina Veterinária, Departamento de Parasitologia Animal, Laboratório de Quimioterapia Experimental em Parasitologia Veterinária - LQEPV, Seropédica, RJ, Brasil.
Eduardo Fellipe Melo Santos SoaresUniversidade Federal Rural Rio de Janeiro, Instituto de Medicina Veterinária, Departamento de Parasitologia Animal, Laboratório de Quimioterapia Experimental em Parasitologia Veterinária - LQEPV, Seropédica, RJ, Brasil.ORCID http://orcid.org/0000-0001-6057-9649
Breno Cayeiro CruzOurofino Saúde Animal Ltda, Cravinhos, SP, Brasil.
Gabriela Pereira Salça de AlmeidaUniversidade Federal Rural Rio de Janeiro, Instituto de Medicina Veterinária, Departamento de Parasitologia Animal, Laboratório de Quimioterapia Experimental em Parasitologia Veterinária - LQEPV, Seropédica, RJ, Brasil.
Gessica Ariane de Melo CruzOurofino Saúde Animal Ltda, Cravinhos, SP, Brasil.
Milenni Garcia MichelsOurofino Saúde Animal Ltda, Cravinhos, SP, Brasil.
Ferdinando Nielsen de AlmeidaOurofino Saúde Animal Ltda, Cravinhos, SP, Brasil.
Igor Renan Honorato GattoOurofino Saúde Animal Ltda, Cravinhos, SP, Brasil.
Thais Ribeiro CorreiaUniversidade Federal Rural Rio de Janeiro, Instituto de Medicina Veterinária, Departamento de Parasitologia Animal, Laboratório de Quimioterapia Experimental em Parasitologia Veterinária - LQEPV, Seropédica, RJ, Brasil.
Fabio Barbour ScottUniversidade Federal Rural Rio de Janeiro, Instituto de Medicina Veterinária, Departamento de Parasitologia Animal, Laboratório de Quimioterapia Experimental em Parasitologia Veterinária - LQEPV, Seropédica, RJ, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lice and mange represent common ectoparasitic infestations in domestic cats, affecting their health and well-being. The study evaluated the efficacy of a topical formulation containing 12.5% fipronil + 0.83% moxidectin + 8.3% praziquantel against common feline ectoparasites Otodectes cynotis, Notoedres cati and Felicola subrostratus. For the ear mite study, a controlled trial was conducted on cats naturally infested with O. cynotis. For the other two parasites, field studies were conducted on naturally infested cats. Cats in the treated group received a single topical dose of formulation. Parasite counts were performed at various time points post-treatment to assess efficacy. The results demonstrated the formulation was highly effective against all three parasites, achieving 100% efficacy after 3 days of treatment. The product was well-tolerated and safe, making it a suitable option for the treatment of feline ectoparasitosis.

Indexed as

AnthelminticsCat DiseasesEctoparasitic InfestationsInsecticidesLice InfestationsMacrolidesMite InfestationsPraziquantelPyrazolesAdministration, TopicalAnimalsCatsDrug CombinationsFemaleMaleAnthelminticsDrug CombinationsfipronilInsecticidesMacrolidesmoxidectinPraziquantelPyrazoles

Identifiers

PMID41983805
PMCPMC13078141

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.