Evidence map›Paper›PMID 41983796›Full record

ArticleBrazilian dental journal2026

Bleaching efficacy and enamel effects of tricalcium phosphate dentifrices containing charcoal or hydrogen peroxide.

Guilherme Silva Dos Santos, Amanda Ferreira Felix, Iago César Ribeiro Teles Matos, Matheus Kury, Vanessa Cavalli

Abstract read
In one paragraph

Article in Brazilian dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Guilherme Silva Dos SantosOperative Dentistry Division, Department of Restorative Dentistry, State University of Campinas, Piracicaba Dental School, 901 Limeira Avenue, Piracicaba, São Paulo 13414-903, Brazil.ORCID 0009-0000-3276-6076
Amanda Ferreira FelixOperative Dentistry Division, Department of Restorative Dentistry, State University of Campinas, Piracicaba Dental School, 901 Limeira Avenue, Piracicaba, São Paulo 13414-903, Brazil.ORCID 0000-0003-2163-7986
Iago César Ribeiro Teles MatosOperative Dentistry Division, Department of Restorative Dentistry, State University of Campinas, Piracicaba Dental School, 901 Limeira Avenue, Piracicaba, São Paulo 13414-903, Brazil.ORCID 0000-0001-9974-2984
Matheus KuryDental Research Division, School of Dentistry, Paulista University, São Paulo, SP, Brazil. 1212.ORCID 0000-0002-9971-0568
Vanessa CavalliOperative Dentistry Division, Department of Restorative Dentistry, State University of Campinas, Piracicaba Dental School, 901 Limeira Avenue, Piracicaba, São Paulo 13414-903, Brazil.ORCID 0000-0002-9459-1926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the bleaching efficacy and effects of dentifrices containing tricalcium phosphate (TCP) with activated charcoal (COAL) or hydrogen peroxide (HP) on dental enamel, compared with monofluorophosphate (MFP). Bovine enamel-dentin discs (n=10/groups) were stained and divided into TCP/HP, TCP/COAL, MFP/HP, MFP/COAL, and C (control - remineralizing solution) groups. Simulated toothbrushing (5.000 cycles) was performed, representing 6 months of clinical condition. The whiteness index (ΔWID), color changes (ΔE00, ΔL, Δa, and Δb), and surface microhardness and roughness (SMH, Ra) were evaluated after staining and treatments. Morphology and mineral content were analyzed under scanning electron microscopy and energy-dispersive X-ray spectroscopy. Data were analyzed using ANOVA/Tukey or Bonferroni tests (α=5%). MFP/COAL demonstrated significantly higher Δa and Δb than C. A statistically significant difference was observed in the TCP groups only for Δa. MFP-containing groups exhibited significantly higher ΔE00 than C. All groups showed negative ΔWID. MFP/COAL promoted greater darkening than TCP-containing and C groups (p<0.05). No statistical difference was detected among groups for ΔL, SMH, Ra, and %SHL (microhardness loss) (p>0.05). No morphological alterations were observed. TCP/HP showed lower mean Ca/P values. Therefore, dentifrices containing TCP associated with HP or COAL showed no bleaching efficacy and no harmful impact on enamel surface properties.

Indexed as

Calcium PhosphatesCharcoalDental EnamelDentifricesHydrogen PeroxideTooth BleachingTooth Bleaching AgentsAnimalsCattleFluoridesMicroscopy, Electron, ScanningPhosphatesSpectrometry, X-Ray EmissionSurface PropertiesCalcium PhosphatesCharcoalDentifricesFluoridesfluorophosphateHydrogen PeroxidePhosphatesTooth Bleaching Agentstricalcium phosphate

Identifiers

PMID41983796
PMCPMC13078688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.