Evidence map›Paper›PMID 41983628›Full record

ArticlePediatrics international : official journal of the Japan Pediatric Society

Licorice-Induced Pseudoaldosteronism Caused by Rikkunshito in an Extremely Low Birth Weight Infant.

Toshihiro Nakayama, Naofumi Hanyu, Shonosuke Nara, Takashi Yamazaki, Gaku Yamanaka

Abstract readCase Reports
In one paragraph

Article in Pediatrics international : official journal of the Japan Pediatric Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Toshihiro NakayamaDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan.ORCID https://orcid.org/0009-0000-7338-6133
Naofumi HanyuDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan.ORCID https://orcid.org/0009-0005-3064-5808
Shonosuke NaraDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan.ORCID https://orcid.org/0009-0003-0083-059X
Takashi YamazakiDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan.ORCID https://orcid.org/0000-0002-4644-3136
Gaku YamanakaDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8379-7187

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report an extremely low birth weight infant with gastroesophageal reflux disease who developed persistent hypokalemia and metabolic alkalosis after treatment with rikkunshito. These findings gradually resolved after discontinuation of rikkunshito and potassium supplementation, suggesting licorice-induced pseudoaldosteronism.

Indexed as

Drugs, Chinese HerbalGlycyrrhizaInfant, Extremely Low Birth WeightFemaleGastroesophageal RefluxHumansHypokalemiaInfant, NewbornDrugs, Chinese Herballiu-jun-zi-tangextremely low birth weight infantgastroesophageal reflux diseasehypokalemiaKampometabolic side effects of drugs

Identifiers

PMID41983628
PMCPMC13081764

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.