Observational studyAnesthesiology2026
Electroencephalographic Monitoring in the Recovery Room for Identification of Patients at Risk for Postoperative Delirium.
Observational study in Anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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Abstract
backgroundElectroencephalography (EEG), especially the assessment of alpha oscillations (8 to 12 Hz), has gained attention as a noninvasive marker of neural network integrity, with reduced alpha power linked to thalamocortical disconnectivity and increased vulnerability to postoperative delirium (POD) in elderly patients. Recent studies have demonstrated that altered EEG dynamics in the alpha-band frequencies during anesthesia emergence in the postanesthesia care unit are associated with POD. However, EEG data postoperatively from the recovery room are scarce.
methodsThis prospective observational study (2019 to 2022) at Charité-Universitätsmedizin Berlin investigates frontal EEG signatures and POD in older adults undergoing surgery. Postoperative POD screening was performed in the recovery room and twice daily for 5 days. While the overall study collected pre- and intraoperative EEGs, this study focused on frontal EEG files recorded in the recovery room while patients were awake. Spectral-domain EEG features and monitor-derived indices were compared by multivariable regression analysis between those who developed POD and those who did not.
resultsA total of 184 patients had sufficient EEG data for analysis; 57 (31%) developed POD. Recovery-room recordings showed significantly reduced alpha- and beta-band power in patients with POD versus those without POD, with cumulative 10- to 20-Hz power providing the best discrimination (area under the receiver operating characteristic, 0.69; 95% CI, 0.60 to 0.77). Patients without POD exhibited increases in alpha- and beta-band power (8 to 20 Hz) relative to preoperative baseline, with the highest augmentation at approximately 16 Hz, whereas POD patients retained spectral patterns comparable to baseline across all frequency bands.
conclusionsThese data suggest that frontal EEG monitoring in the recovery room can help identify a "vulnerable brain" phenotype associated with increased POD risk. Integrating this monitoring into postoperative care may support risk stratification and more individualized management.
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