Evidence map›Paper›PMID 41983354›Full record

ArticleBJS open2025

Development and validation of a short version of the MD Anderson Symptom Inventory for upper gastrointestinal surgery (short-MDASI-UGI-Surg) for postoperative patient-reported outcome-based care.

Taisuke Imamura, Koichi Tomita, Paula Marincola Smith, Maho Takayama, Anneliese Hierl, Xin Shelley Wang, Loretta A Williams, Kyle G Mitchell, Ravi Rajaram, David Rice and 15 more

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BJS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

25 authors.

Taisuke ImamuraDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Koichi TomitaDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0003-2484-6548
Paula Marincola SmithDepartment of Department of Colon & Rectal Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Maho TakayamaDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Anneliese HierlDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Xin Shelley WangDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Loretta A WilliamsDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Kyle G MitchellDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Ravi RajaramDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
David RiceDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Wayne HofstetterDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Mara B AntonoffDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Reza MehranDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Ara VaporciyanDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Garrett WalshDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Jessica E MaxwellDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Rebecca A SnyderDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Michael P KimDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Ching-Wei D TzengDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Paul MansfieldDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Stephen SwisherDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Jeffrey E LeeDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Brian D BadgwellDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Matthew H G KatzDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0003-3870-6968
Naruhiko IkomaDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-9825-9234

Funding

Andrew Sabin Family FoundationIntuitive Surgical Clinical Research 2021Project Periwinkle Research 2021Project Periwinkle Research 2022The University of Texas MD Anderson Cancer Center
6 · The paper itself

Abstract

backgroundThe MD Anderson Symptom Inventory for upper gastrointestinal surgery (MDASI-UGI-Surg) is a validated 27-item patient-reported outcome instrument designed to assess perioperative symptom burden and functional status in patients undergoing surgery for upper gastrointestinal cancers. This study aimed to develop a shortened version (Short-MDASI-UGI-Surg) that preserves the sensitivity of the original tool while reducing respondent burden.

methodsProspectively collected longitudinal patient-reported outcome data obtained using the MDASI-UGI-Surg or the MDASI in patients with gastrointestinal cancer (MDASI-GI) from patients who underwent oesophagectomy, gastrectomy, or pancreatectomy for cancer were retrospectively analysed. Symptom severity and temporal patterns were examined using hierarchical clustering, and representative symptoms were selected based on clinical relevance and symptom severity through correlation analysis.

resultsTime series clustering of the 27 items collected from 302 patients revealed three distinct symptom/interference clusters based on relative peak timing: acute, with items peaking on postoperative day (POD) 3; subacute, peaking on POD 21; and persistent, extending through postoperative months 3-6. Within each symptom/interference cluster, items were identified that were highly correlated with other items (r ≥ 0.55), from which 13 representative symptom or interference items were selected. The 13 selected items were incorporated into the Short-MDASI-UGI-Surg and demonstrated high concurrent validity with the harmonized full MDASI reference (r = 0.98) and strong concordance in time series trends across all timepoints (r = 0.96-0.98). Known groups validity was supported by significant differences in scores between the oesophagectomy, pancreatectomy, and gastrectomy groups using both the harmonized full MDASI instrument and the Short-MDASI-UGI-Surg.

conclusionsThe 13-item Short-MDASI-UGI-Surg, may reduce respondent burden and enhance clinical implementation while promoting patient engagement in perioperative symptom monitoring.

Indexed as

Digestive System Surgical ProceduresGastrointestinal NeoplasmsPatient Reported Outcome MeasuresAdultAgedEsophagectomyFemaleGastrectomyHumansLongitudinal StudiesMaleMiddle AgedPancreatectomyPostoperative ComplicationsReproducibility of ResultsRetrospective Studiesgastrointestinal cancerlongitudinal assessmentperioperative caresymptom burden

Identifiers

PMID41983354
PMCPMC13080355

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