ArticleTherapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy2026
Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients.
Article in Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionPeritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI).
methodsDPI was assessed from 24-h dietary recall using Nutrics software. Total protein losses were measured in 24-h collections of spent dialysate and urine.
resultsWe studied, 41 patients, mean age 62.2 ± 15.8 years, 56.1% male, treated for 14.0 (3-23) months. Only13 (31.7%) met the recommended DPI target of ≥ 1.0 g/kg/day, and they had greater peritoneal protein losses 5.2 ± 2.4 versus 3.3 ± 1.1 g/day, p < 0.001, and faster peritoneal solute transfer rates (PTSR ×100 for protein 0.93 (0.58-1.21) versus 0.44 (0.35-0.56), p < 0.001). On multivariate analysis DPI was associated with calorie intake (standardized beta coefficient (Stꞵ) 0.56, p < 0.001, and peritoneal protein clearance rate (Stꞵ 0.36, p = 0.002).
conclusionPatients with faster protein clearance and protein losses had higher DPI.
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