Evidence map›Paper›PMID 41983266›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Diminished Signal-to-Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1

Ourania Semelidou, Théo Gauvrit, Célien Vandromme, Alexandre Cornier, Anna Saint-Jean, Yves Le Feuvre, Melanie Ginger, Andreas Frick

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ourania SemelidouUniversity of Bordeaux, INSERM, Neurocentre Magendie, Bordeaux, France.ORCID https://orcid.org/0000-0001-8774-6013
Théo GauvritUniversity of Bordeaux, INSERM, Neurocentre Magendie, Bordeaux, France.
Célien VandrommeUniversity of Bordeaux, INSERM, Neurocentre Magendie, Bordeaux, France.
Alexandre CornierUniversity of Bordeaux, INSERM, Neurocentre Magendie, Bordeaux, France.
Anna Saint-JeanUniversity of Bordeaux, INSERM, Neurocentre Magendie, Bordeaux, France.
Yves Le FeuvreUniversity of Bordeaux, INSERM, Neurocentre Magendie, Bordeaux, France.
Melanie GingerUniversity of Bordeaux, INSERM, Neurocentre Magendie, Bordeaux, France.
Andreas FrickUniversity of Bordeaux, INSERM, Neurocentre Magendie, Bordeaux, France.ORCID https://orcid.org/0000-0002-1392-0995

Funding

Agence Nationale de la Recherche ANR-EMT-SensANR-EMT-SensANR-MultiSensBrain and Behavior Research Foundation Young Investigator 32694Foundation for Brain Research (FRC)Foundation for Medical Research (FRM) postdoc fellowship SPF202005011992Marcel Dassault-Fondation FondaMental Award 2019NeuroCentre Magendie INSERM U1215Simons Foundation Autism Research Initiative
6 · The paper itself

Abstract

Touch is essential for interacting with the world, and atypical tactile experience is a core feature of autism that profoundly affects daily life. However, we do not know the neural mechanisms of low-level tactile perception and their alterations in autism. Using a translational forepaw-based perceptual task, we recapitulate the multifaceted tactile features of autistic individuals in the Fmr1

Indexed as

Autistic DisorderFragile X Messenger Ribonucleoprotein 1Somatosensory CortexTouchTouch PerceptionAnimalsDisease Models, AnimalHumansMaleMiceNeuronsSignal-To-Noise RatioFmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1calcium imaginghyposensitivitymouse model of autismneural mechanismsperceptual decision‐makingsignal‐to‐noise ratiotactile perception

Identifiers

PMID41983266
PMCPMC13185836

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.