ArticleDigestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society2026
Perforating Veins Detected by Endoscopic Ultrasonography Are Useful in Predicting the Recurrence of Esophageal Varices After Endoscopic Variceal Ligation Combined With Argon Plasma Coagulation.
Article in Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Importance of Endoscopic Ultrasound After Treatment of Esophageal Varices.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Article
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11 authors.
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Abstract
objectivesFew attempts have been made to determine the risk factors for the recurrence of esophageal varices (EV) and the optimal surveillance interval. This study analyzed whether endoscopic ultrasonography can be used to predict EV recurrence and determine the optimal timing for surveillance endoscopy post-treatment.
methodsWe retrospectively evaluated patients with EVs who underwent endoscopic variceal ligation (EVL) combined with argon plasma coagulation (APC), followed by endoscopic ultrasonography (EUS) using a miniature ultrasonic probe 1 month after APC. Factors associated with EV recurrence were assessed using the Fine-Gray competing risk regression model, with death considered as the competing risk. The cumulative incidence of EV recurrence was estimated using the cumulative incidence function, and groups were compared using Gray's test.
resultsOf 163 eligible patients, 37 (23%) experienced EV recurrence during a median follow-up period of 36 months (interquartile range: 15-76 months). Multivariable analysis revealed that the presence of perforating veins (PVs) was a significant factor for EV recurrence (sub-distribution hazard ratio, 4.30; 95% confidence interval, 2.13-8.71; p < 0.001). The cumulative incidence of EV recurrence was significantly higher in patients with PV than in those without (6-month and 1-year recurrence rates: 27.3% and 41.6% vs. 3.9% and 5.5%, respectively; p < 0.001).
conclusionsPVs detected using EUS independently predict EV recurrence risk after EVL combined with APC. Given that patients with PVs experience a high recurrence rate within 6 months, comprehensive surveillance endoscopy at 6-month intervals is recommended in the first year post-treatment.
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