Influence of molecular shape and hydrogen bonding on glycolipid self-assembly into thermotropic gyroid phases.

Soumi Das, Caini Zheng, Timothy P Lodge, J Ilja Siepmann, Michelle A Calabrese, Theresa M Reineke

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In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Soumi DasDepartment of Chemistry, University of Minnesota Twin Cities 207 Pleasant St SE Minneapolis MN 55455 USA treineke@umn.edu mcalab@umn.edu.ORCID https://orcid.org/0000-0002-0646-0513

Caini ZhengDepartment of Chemistry, University of Minnesota Twin Cities 207 Pleasant St SE Minneapolis MN 55455 USA treineke@umn.edu mcalab@umn.edu.

Timothy P LodgeDepartment of Chemistry, University of Minnesota Twin Cities 207 Pleasant St SE Minneapolis MN 55455 USA treineke@umn.edu mcalab@umn.edu.ORCID https://orcid.org/0000-0001-5916-8834

J Ilja SiepmannDepartment of Chemistry, University of Minnesota Twin Cities 207 Pleasant St SE Minneapolis MN 55455 USA treineke@umn.edu mcalab@umn.edu.ORCID https://orcid.org/0000-0003-2534-4507

Michelle A CalabreseDepartment of Chemical Engineering and Materials Science, University of Minnesota Twin Cities 421 Washington Ave SE #151 Minneapolis MN 55455 USA.ORCID https://orcid.org/0000-0003-4577-6999

Theresa M ReinekeDepartment of Chemistry, University of Minnesota Twin Cities 207 Pleasant St SE Minneapolis MN 55455 USA treineke@umn.edu mcalab@umn.edu.ORCID https://orcid.org/0000-0001-7020-3450

Funding

Skin-targeted Cell Therapy for Recessive Dystrophic Epidermolysis BullosaR01AR063070 · NIAMS · UNIVERSITY OF MINNESOTA · PI Mark J Osborn, Jakub Tolar · 2013 to 2026

$4.5M

NIAMS NIH HHS R01 AR063070

6 · The paper itself

Abstract

Periodic network morphologies such as the double gyroid (DG) are promising for a wide range of applications, from optical materials and organic semiconductors to separation membranes and drug delivery vehicles. While natural glycolipids are a constituent of cell membranes, synthetic glycolipids have emerged as candidates for producing thermotropic DG phases with sub-5 nm domains. Despite this potential, difficulties in producing stereochemically-pure glycolipids and a lack of known design rules governing DG self-assembly limit their broad use. Our recent work identified two key factors stabilizing DG in ten anomerically pure Guerbet cellobiosides: a bent molecular topology and moderate hydrogen bonding between sugar headgroups. However, the influence of glycolipid shape

Identifiers

PMID41982930

DOI10.1039/d6sc00024j

PMCPMC13071426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.