ArticleChemical science2026
Core-wing modulated squaraines with enhanced two-photon absorption and efficient photothermal eradication of bacteria.
Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Predictable structure-property relationships for near-infrared (NIR)-emitting chromophores and sustainable photothermal agents remain challenging. Herein, two series of indolenine-based squaraines are synthesized to investigate how core-wing structural modulation influences photophysical properties. Dicyanovinylene modification of the squaraine carbonyl core induces a substantial bathochromic shift and enriches de-activation pathways, while further wing functionalization strengthens intramolecular charge transfer (ICT) efficiency and enhances nonlinear two-photon absorption (2PA). Intrinsic zwitterionic stabilization and the bent-shaped molecular skeleton of bis(dicyanovinylene)-cored squaraines are also supported by theoretical calculations. Optimal benzindolenine-winged squaraine dye SQ2-4CN demonstrates a strong two-photon absorption cross-section (
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