ArticleFrontiers in microbiology2026
Phylogenetic divergence drives distinct antimicrobial susceptibility profiles and resistomes in
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Methods: In this study, the antibiotic susceptibility of 21 average nucleotide identity (ANI) species that were relatively evenly distributed across the genus-level ANI clustering tree was tested, and the relationship between the antibiotic resistance gene profiles and phylogenetic divergence was investigated. Results: Among the 17 drugs tested, tigecycline showed 100% susceptibility, followed by chloramphenicol and trimethoprim-sulfamethoxazole (7.69% resistance). Cefotaxime had the highest resistance (97.44%), while ceftazidime and ceftazidime/avibactam showed 41.03% resistance. The overall multidrug resistance (MDR) rate was 74.36%. All strains harbored the SmeTDEF and AdeFGH multidrug efflux systems, while Smc-sgn strains commonly carried class A and B β-lactamases ( Conclusion: Based on this study, preliminary insights into the comprehensive antibiotic resistance profiles and genetic mechanisms of
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