Evidence map›Paper›PMID 41982743›Full record

ArticleFrontiers in dental medicine2026

Comprehensive evaluation of antibacterial activity, pH stability, and surface characterization of a mussel-inspired polymer for root perforation repair.

Lakshmi Nidhi Rao, Aditya Shetty, Veena Shetty, Heeresh Shetty

Abstract read
In one paragraph

Article in Frontiers in dental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lakshmi Nidhi RaoDepartment of Conservative Dentistry and Endodontics, NITTE (Deemed to be University) AB Shetty Memorial Institute of Dental Sciences, Mangaluru, India.
Aditya ShettyDepartment of Conservative Dentistry and Endodontics, NITTE (Deemed to be University) AB Shetty Memorial Institute of Dental Sciences, Mangaluru, India.
Veena ShettyDepartment of Microbiology, K S Hegde Medical Academy, NITTE (Deemed to be University), Mangaluru, India.
Heeresh ShettyDepartment of Conservative Dentistry and Endodontics, Nair Hospital Dental College, Mumbai, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Root perforation is a serious complication in endodontic therapy that can adversely affect treatment outcomes due to persistent microbial contamination and the limitations of currently available repair materials. Although mineral trioxide aggregate (MTA) is widely used, its handling characteristics, prolonged setting time, and variable antibacterial activity necessitate the development of alternative materials. This study evaluated a novel bio-inspired composite combining polydopamine, a mussel-derived adhesive polymer, with bioactive glass, designed to enhance antibacterial performance, surface characteristics, and pH behaviour relevant to root perforation repair. It was hypothesized that the experimental composite would exhibit improved antibacterial efficacy and a favourable surface nanoarchitecture compared with MTA, while maintaining physiologically relevant alkalinity. Antibacterial activity was assessed using agar diffusion against Porphyromonas endodontalis and Enterococcus faecalis, pH was measured at 24 h and 7 days, and surface characteristics were analysed using atomic force microscopy and field emission scanning electron microscopy. Antibacterial outcomes were compared using the Mann-Whitney

Indexed as

antibacterial activitybioactive glasspHpolydopamineroot perforation repair

Identifiers

PMID41982743
PMCPMC13070965

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.