Evidence map›Paper›PMID 41982662›Full record

SynthesisFrontiers in pharmacology2026

Effects of schisandra extract on muscle atrophy: a systematic review and meta-analysis of preclinical studies.

Xiao Liu, Chen Wang, Qi Song, Hai Liu, Youkang Zhu, Zhaochuan Xu, Xifang Liu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiao LiuDepartment of Rehabilitation, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shanxi, China.
Chen WangDepartment of Rehabilitation, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shanxi, China.
Qi SongDepartment of Rehabilitation, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shanxi, China.
Hai LiuDepartment of Rehabilitation, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shanxi, China.
Youkang ZhuDepartment of Rehabilitation, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shanxi, China.
Zhaochuan XuDepartment of Rehabilitation, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shanxi, China.
Xifang LiuDepartment of Rehabilitation, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lignans from Objective: This meta-analysis evaluates the effects of Methods: We systematically searched PubMed, Web of Science, Embase, Cochrane Library, and Ovid from inception to April 2025 for relevant animal RCTs, selected via the PICOS framework. Study quality was assessed using the SYRCLE tool. A random-effects meta-analysis was performed on outcomes including muscle weight, fiber cross-sectional area (CSA), catalase (CAT) activity, and grip strength. Results: Eleven studies (149 experimental, 149 control animals) were included. Conclusion: Systematic Review Registration: identifier INPLASY202590030.

Indexed as

animal modelsmeta-analysismuscle atrophyoxidative stressschisandra

Identifiers

PMID41982662
PMCPMC13071297

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.