Evidence map›Paper›PMID 41982634›Full record

ReviewHealth affairs scholar2026

Racial disparities in drug toxicology testing among pregnant women & infants: a meta-analysis and systematic review.

Sugy Choi, Elizabeth Knopf, Kwanbo Shim, Megan Sanico, Erinn M Hade, Mishka Terplan, Davida Schiff, Leah Habersham, Carolyn A Berry, Charles J Neighbors and 1 more

Abstract readReview
In one paragraph

Review in Health affairs scholar, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sugy ChoiDepartment of Population Health, New York University Grossman School of Medicine, New York, NY 10016, United States.ORCID https://orcid.org/0000-0002-5549-2861
Elizabeth KnopfDepartment of Population Health, New York University Grossman School of Medicine, New York, NY 10016, United States.
Kwanbo ShimDepartment of Population Health, New York University Grossman School of Medicine, New York, NY 10016, United States.ORCID https://orcid.org/0009-0007-8590-1279
Megan SanicoSchool of Public Health, University of Illinois Chicago, Chicago, IL 60607, United States.ORCID https://orcid.org/0009-0007-7935-3464
Erinn M HadeDepartment of Population Health, New York University Grossman School of Medicine, New York, NY 10016, United States.ORCID https://orcid.org/0000-0001-8977-6443
Mishka TerplanFriends Research Institute, Baltimore, MD 21201, United States.
Davida SchiffDivisions of General Academic Pediatrics and Newborn Medicine, Mass General for Children, Boston, MA 02114, United States.ORCID https://orcid.org/0000-0002-6435-1016
Leah HabershamDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.ORCID https://orcid.org/0000-0002-1561-5265
Carolyn A BerryDepartment of Population Health, New York University Grossman School of Medicine, New York, NY 10016, United States.ORCID https://orcid.org/0000-0003-3671-3080
Charles J NeighborsDepartment of Population Health, New York University Grossman School of Medicine, New York, NY 10016, United States.ORCID https://orcid.org/0000-0002-9163-8389
Jennifer McNeelyDepartment of Population Health, New York University Grossman School of Medicine, New York, NY 10016, United States.ORCID https://orcid.org/0000-0003-4601-6940

Funding

Multi-Level Analysis of Perinatal Toxicology Practices in New York State: An Explanatory-Sequential Mixed-Methods StudyK01DA063748 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Sugy Choi · 2025 to 2026
$417k
NIDA NIH HHS K01 DA063748
6 · The paper itself

Abstract

Introduction: We synthesized evidence on racial disparities in perinatal toxicology testing among Black and White women and their infants in the United States, including testing practices and downstream consequences such as child welfare involvement. Methods: We systematically searched PubMed and PsycINFO for peer-reviewed studies published before January 2023 that examined perinatal toxicology testing and reported racial outcomes. Eligible studies assessed testing practices or related consequences. A random-effects meta-analysis estimated pooled rate ratios (RRs) and 95% confidence intervals (CIs) for disparities in testing. Thematic synthesis summarized qualitative findings on downstream outcomes. Sixteen studies (1993-2023) met inclusion criteria; six contributed to the meta-analysis, encompassing over 50 000 pregnant women and/or their infants. Results: Black women and their infants were significantly more likely to be tested than their White counterparts (RR = 2.58; 95% CI: 2.03-3.29). While recent studies suggest disparities in referral to child welfare services after positive tests may be narrowing, earlier research indicates disproportionate reporting and child removal among Black and Hispanic families. Conclusion: Racial inequities in perinatal and infant toxicology testing persist, with implications for maternal and child health. Future research should investigate multilevel drivers of these disparities and inform equitable policy and practice.

Indexed as

Behavioral healthChild protective servicesChild welfare systemPublic healthRacismSubstance use research

Identifiers

PMID41982634
PMCPMC13071810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.