Evidence map›Paper›PMID 41982416›Full record

ArticleFrontiers in neurology

The effect of hyperbaric oxygen therapy on sleep quality across diverse patient populations.

Keren Doenyas-Barak, Karin Elman Shina, Erez Lang, Shachar Finci, Vicktoria Elkarif, Ran Shorer, Shai Efrati

Abstract read
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Keren Doenyas-BarakYitzhak Shamir Medical Center, Tel Aviv, Israel.
Karin Elman ShinaYitzhak Shamir Medical Center, Tel Aviv, Israel.
Erez LangYitzhak Shamir Medical Center, Tel Aviv, Israel.
Shachar FinciYitzhak Shamir Medical Center, Tel Aviv, Israel.
Vicktoria ElkarifYitzhak Shamir Medical Center, Tel Aviv, Israel.
Ran ShorerYitzhak Shamir Medical Center, Tel Aviv, Israel.
Shai EfratiYitzhak Shamir Medical Center, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sleep disturbances are common in aging, post-traumatic stress disorder (PTSD), and long COVID, often linked to neuroinflammation, autonomic dysregulation, and neurodegeneration. Hyperbaric oxygen therapy (HBOT) promotes neuroplasticity through the hyperoxic-hypoxic paradox, improving cerebral perfusion, mitochondrial function, and reducing inflammation. While HBOT benefits sleep in certain conditions, its general effects across clinical populations remain unclear. Methods: This retrospective longitudinal study evaluated Pittsburgh Sleep Quality Index (PSQI) changes in patients undergoing 60 HBOT sessions (2.0 ATA, 100% oxygen, 90 min, 5 days/week) at the Sagol Center. Participants included individuals treated for healthy aging ( Results: Among 395 patients (mean age at baseline 57.9 ± 14.6 years, 31% female), baseline PSQI scores were highest in PTSD. Post-HBOT, total PSQI scores improved significantly in all groups ( Conclusion: HBOT was associated with improvement in sleep quality across diverse conditions, with greatest benefit in patients with poorer baseline sleep. Findings support HBOT's potential as a sleep-modulating therapy, warranting controlled trials to characterize the patients that can benefit the most and elucidate mechanisms.

Indexed as

agingCOVID-19hyperbaric oxygen (HBO) therapyneuroplasticityPittsburgh Sleep Quality Index (PSQI)PTSDsleep

Identifiers

PMID41982416
PMCPMC13070804

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.