Evidence map›Paper›PMID 41982306›Full record

ArticleJAMIA open2026

Evolving language of pediatric anxiety in electronic health records.

Jordan Tschida, Mayanka Chandrashekar, Heidi A Hanson, Ian Goethert, Daniel Santel, John Pestian, Jeffery R Strawn, Tracy Glauser, Anuj J Kapadia, Greeshma A Agasthya

Abstract read
In one paragraph

Article in JAMIA open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jordan TschidaCyber Resilience and Intelligence, Oak Ridge National Laboratory, Oak Ridge, TN, 37830, United States.ORCID https://orcid.org/0000-0002-1359-4165
Mayanka ChandrashekarAdvanced Computing for Health Sciences, Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37830, United States.ORCID https://orcid.org/0000-0002-3697-5972
Heidi A HansonAdvanced Computing for Health Sciences, Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37830, United States.
Ian GoethertInformation Technology Services Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37830, United States.
Daniel SantelDivision of Biomedical Informatics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States.
John PestianDivision of Biomedical Informatics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States.
Jeffery R StrawnDepartment of Psychiatry, University of Cincinnati, Cincinnati, OH, 45221, United States.
Tracy GlauserDivision of Neurology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, 45229, United States.
Anuj J KapadiaAdvanced Computing for Health Sciences, Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37830, United States.
Greeshma A AgasthyaAdvanced Computing for Health Sciences, Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37830, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to identify and quantify semantic drift (ie, the change in semantic meaning over time) within expert-defined anxiety-related (AR) terminology and compare it to common electronic health record (EHR) vocabulary across longitudinal pediatric clinical notes. Materials and Methods: A corpus of pediatric clinical notes from 2009 to 2022 was analyzed using computational methods. Semantic drift for each term was quantified using cosine similarity between annual temporal word embeddings. Contextual meaning was examined through changes in nearest neighbors across years. The Laws of Semantic Change were applied to assess the influence of word frequency and polysemy. Vocabulary terms were categorized as AR or common EHR. Results: 98% of AR terminology maintained a cosine similarity between 0.00 and 0.50, indicating moderate semantic stability, whereas 90% of common EHR terms remained between 0.00 and 0.25, showing greater contextual stability overall. Frequent terms exhibited minimal change (Frequency Coefficient = 0.04), whereas highly polysemous or abbreviated terms showed less stability (Polysemy Coefficient = 0.630). AR terminology drifted more slowly than general EHR vocabulary (Type Coefficient = -0.179), further supported by significant year-type interactions (Coef = -0.09 to -0.523). Discussion: Although anxiety-related terminology demonstrates slower semantic drift than general EHR vocabulary, subtle contextual shifts still occur that may affect downstream interpretability and retrieval in automated systems. Conclusion: Continuous linguistic monitoring and adaptive modeling are essential to maintain semantic fidelity and ensure the long-term reliability of clinical decision support systems as healthcare documentation evolves.

Indexed as

clinical natural language processingelectronic health recordsPediatric anxiety disorderssemantic drifttemporal word embeddings

Identifiers

PMID41982306
PMCPMC13071396

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.