SynthesisFrontiers in oncology2026
Burden, clinical characteristics, and management patterns of prostate cancer in Nigeria: a systematic review and meta-analysis.
Synthesis in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Prostate cancer is one of the most common types of cancer morbidity and mortality among Nigerian men, but there are still limited comprehensive epidemiological data. Understanding the hospital-based patterns of prostate cancer burden, risk factor distributions, and treatment modalities is paramount in supporting policy, clinical practice, and resource allocation in the healthcare system of Nigeria. Purpose: The aim of the systematic review and meta-analysis was to summarize information regarding the burden, clinical features, and management patterns of prostate cancer in Nigeria. Methods: A systematic review and meta-analysis conducted in PRISMA 2020 were implemented. PubMed, Scopus, Web of Science, and Google Scholar were searched since January 2000. Research studies that had reported prostate cancer percentage, risk, or treatment patterns among Nigerian men were eligible. Results: 32 studies (19,050 participants) were included, mainly retrospective (44.1) and cross-sectional (41.2), mostly hospital-based (82.4) and were done in Southwest and south-south Nigeria. In 70.6% of the cases, the diagnosis was confirmed using histology. The combined percentage of prostate cancer was 16.4 in hospital-based researches (95% CI: 8.6%29.2; I 2 = 99.3) and 14.0 in population-based research (95% CI: 4.1 - 40.0%; I Conclusions: Prostate cancer is a significant problem in healthcare facilities of Nigeria, and radical heterogeneity along with methodological constraints make it impossible to make conclusive estimates regarding prevalence. Existing health disparities and insufficient access to curative therapies are also distinctive to the areas. Cancer control policies in Nigeria are in urgent need of population-based cancer registries, multicentre cohort studies, and implementation research to inform evidence-based cancer control policies. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD420261325315.
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