ArticleBreast cancer (Dove Medical Press)2026
Analysis of Factors Related to Lymph Node Metastasis Following Neoadjuvant Chemotherapy for Breast Cancer: Correlation Between Plasma Exosomal Circular RNA and Metastasis.
Article in Breast cancer (Dove Medical Press), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Exploring the Clinical Transformation of circRNA as a Biomarker in Breast Cancer.Cancer control : journal of the Moffitt Cancer CenterReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the correlation between plasma exosomal circular RNA (circRNA) (non-invasive, dynamically monitorable) and lymph node metastasis following neoadjuvant chemotherapy in breast cancer and highlight its predictive superiority over traditional serum markers. Methods: The clinicopathological data and follow-up data of 487 patients with breast cancer who received neoadjuvant therapy in our hospital between 1 January 2018 and 1 January 2020 were retrospectively collected using convenience sampling. Following screening, 379 patients who met the inclusion and exclusion criteria were included in the analysis. The patients' data, including age, clinical TNM stage, tumour pathological type, tumour histological grade, tumour molecular typing, neoadjuvant regimen and course of treatment, were collected for analysis. Results: Log rank test results showed that there were significant differences between the two groups in molecular typing (χ Conclusion: Molecular typing, pCR status, histological grade and plasma exosomal circRNA expression level are independent predictors of recurrence and metastasis following neoadjuvant therapy. Notably, plasma exosomal circRNA, with its non-invasive and dynamic monitoring advantages, shows promising predictive potential for lymph node metastasis, providing a novel and superior clinical tool for prognosis assessment.
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