Evidence map›Paper›PMID 41982206›Full record

ArticleActa odontologica Scandinavica2026

Gestational diabetes alters subgingival pathobiont composition.

Fatih Cömert, Funda Yalçın, Nursen Topçuoğlu, Oya Kaya-Şimşek, Oya Demirci, Silvi Domnori, Ulku Baser

Abstract read
In one paragraph

Article in Acta odontologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatih CömertDepartment of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Türkiye.
Funda YalçınDepartment of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Türkiye.
Nursen TopçuoğluDepartment of Oral Microbiology, Faculty of Dentistry, Istanbul University, Istanbul, Türkiye.
Oya Kaya-ŞimşekDepartment of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Türkiye.
Oya DemirciDepartment of Perinatology, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Health Science University, Istanbul, Türkiye.
Silvi DomnoriDepartment of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Türkiye; Department of Periodontology, Faculty of Dentistry, Institute of Graduate Studies in Health Sciences, Istanbul University, Istanbul, Türkiye.
Ulku BaserDepartment of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Türkiye. baserulk@istanbul.edu.tr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis cross-sectional study assesses the relationship between gestational diabetes mellitus (GDM) and periodontal dysbiosis by evaluating specific periodontal pathobionts (Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia, and Treponema denticola), clinical periodontal parameters, and periodontal inflamed surface area (PISA). MATERIALS AND

methods101 GDM and 98 non-GDM women of 16-36 weeks gestation were included. Clinical periodontal parameters were measured, and PISA values calculated. Subgingival plaque samples, collected from the deepest pockets, were analyzed, to assess the amount of periodontopathogens. Associations were assessed using binary logistic regression and path analysis.

resultsThe GDM group showed higher clinical parameters and PISA values (p < 0.001). While P. gingivalis levels were similar in both groups (p = 0.924) and unrelated to the presence of GDM in path analysis (p = 0.055), P. intermedia and T. denticola levels were found higher in the non-GDM group (p < 0.05, p < 0.001) and negatively associated with the presence of GDM (p < 0.001, p = 0.002). P. intermedia increased with gestation week (p = 0.044). Elevated T. forsythia levels were observed to increase GDM risk 1.208-fold in regression analysis (p = 0.002).

conclusionIncreasing sex hormone levels accompanied by the presence of GDM may alter subgingival pathobiont composition. In patients with GDM, there is a heightened burden of T. forsythia in subgingival zones, where P. intermedia finds less favorable conditions.

Indexed as

Diabetes, GestationalAdultCross-Sectional StudiesFemaleHumansPorphyromonas gingivalisPregnancyPrevotella intermediaTannerella forsythiaTreponema denticola

Identifiers

PMID41982206
PMCPMC13088773

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