ArticleNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2026
Single-center experience of the Crohn's disease exclusion diet in the United States: A retrospective study.
Article in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe Crohn's Disease Exclusion Diet (CDED) offers a dietary means of inducing and maintaining remission for patients with Crohn's disease (CD). Descriptions of efficacy have emerged primarily from Israel, Europe, and Canada. Here, we offer real-world experience, from a tertiary care center in the United States.
methodsWe conducted a retrospective chart review of patients receiving education on the CDED and those adopting the diet. Demographics, medication exposure, disease-related complications, and reported side effects were collected. Corticosteroid-free clinical remission (SF-CR) was measured at weeks 6, 12, and 24 via the pediatric Crohn's Disease Activity Index (PCDAI). Biomarkers were collected at baseline and while on the diet.
resultsOnly 8% (n = 32) of children with CD had met with a dietitian regarding the CDED. Of those, 75% (n = 24) adopted the diet. A statistically significant change in PCDAI from baseline to weeks 6, 12, and 24 (χ
conclusionIn this single-center experience of children with mild to moderate CD who adopted the CDED, adherence was a challenge. However, for those who were able to sustain the diet, the CDED offered a safe and effective means of clinical remission.
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