Evidence map›Paper›PMID 41981772›Full record

ArticlePhysiological reports2026

Mature-onset obesity in p62-deficient male mice maintains skeletal muscle mass despite metabolic dysfunction.

Do-Houn Kim, Gloria Salazar, Alex Klemp, Hyun-Seok Hwang, Mingchia Yeh, Lynn B Panton, Jeong-Su Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Do-Houn KimDepartment of Health, Nutrition, and Food Sciences, The Florida State University, Tallahassee, Florida, USA.ORCID 0000-0002-7556-8632
Gloria SalazarDepartment of Health, Nutrition, and Food Sciences, The Florida State University, Tallahassee, Florida, USA.
Alex KlempDepartment of Health, Nutrition, and Food Sciences, The Florida State University, Tallahassee, Florida, USA.
Hyun-Seok HwangDepartment of Biological and Health Sciences, Texas A&M University-Kingsville, Kingsville, Texas, USA.
Mingchia YehDepartment of Exercise Science, Slippery Rock University, Slippery Rock, Pennsylvania, USA.
Lynn B PantonDepartment of Health, Nutrition, and Food Sciences, The Florida State University, Tallahassee, Florida, USA.
Jeong-Su KimDepartment of Health, Nutrition, and Food Sciences, The Florida State University, Tallahassee, Florida, USA.

Funding

Florida State UniversityJiwon Co.
6 · The paper itself

Abstract

Sequestosome 1 (p62/SQSTM1) is a multifunctional scaffolding protein at the intersection of autophagy and metabolic regulation. While p62 deficiency causes mature-onset obesity and insulin resistance, its effects on skeletal muscle mass and function remain poorly understood. Male p62 knockout (p62

Indexed as

Muscle, SkeletalObesitySequestosome-1 ProteinAnimalsAutophagyHand StrengthInsulin ResistanceIntracellular Signaling Peptides and ProteinsMaleMiceMice, Inbred C57BLMice, KnockoutTOR Serine-Threonine KinasesTranscription Factor TFIIHIntracellular Signaling Peptides and ProteinsmTOR protein, mouseNbr1 protein, mouseSequestosome-1 ProteinSqstm1 protein, mouseTOR Serine-Threonine KinasesTranscription Factor TFIIHautophagyinsulin resistancemetabolic dysfunctionmTOR signalingNBR1neuromuscular healthobesitysequestosome 1skeletal muscle preservation

Identifiers

PMID41981772
PMCPMC13079410

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.