Evidence map›Paper›PMID 41981398›Full record

Trial reportBMC anesthesiology2026

Effect of 16-gauge needle as needle-over-needle guidance introducer in single-operator real-time ultrasound-guided spinal anesthesia: a randomized controlled trial.

Qingqing Qian, En Yao Qi, Hongyue He, Rui Ding, Qilian Tan, Hongguang Bao, Tao Shan, Yongjun Li, Hongwei Shi

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qingqing Qian *Department of Anesthesiology, Women's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing, Jiangsu Province, 210001, China.
En Yao Qi *Department of Anesthesiology, Nanjing Luhe People's Hospital, Yangzhou University, Nanjing, Jiangsu Province, 211500, China.
Hongyue He *Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, 210006, China.
Rui Ding *Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, 210006, China.
Qilian TanDepartment of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, 210006, China.
Hongguang Bao *Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, 210006, China.
Tao Shan *Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, 210006, China. shantao2021@163.com.
Yongjun Li *Department of Anesthesiology, Lianshui County People's Hospital, Huaian, Jiangsu Province, 223405, China. 779053808@qq.com.
Hongwei Shi *Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, 210006, China. mdshw@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to evaluate the effect of a 16-gauge needle as an introducer in single-operator real-time ultrasound-guided subarachnoid anesthesia.

methodsOne hundred and two parturients undergoing cesarean section were randomized to undergo real-time ultrasound-guided subarachnoid anesthesia either with (group T) or without (group C) a 16-gauge needle as an introducer. The primary outcome was the number of needle passes required for a successful dural puncture. Secondary outcomes included the number of attempts, first pass/attempt success rate, procedure time, parturients’ pain, puncture depth, periprocedural complications, and the quality of sonographic images.

resultsThe median number of needle passes and attempts were significantly lower in group T than in group C [1 (1–2) vs. 2 (1–3), median difference (95% CI): 1 (0–1), P < 0.001; 1 (1–1) vs. 1 (1–1), median difference (95% CI): 0 (0–0), P = 0.042]. The first pass/attempt success rates in group T were significantly higher than in group C (70.6% vs. 35.3%, 100% vs. 88.2%; both, P < 0.001). The total procedural time was shorter in group T [108 (94–130) vs. 123 (100–163) seconds, median difference (95% CI): 15 (3–33), P < 0.016]. No intergroup differences of pain, puncture depth, periprocedural complications and quality of sonographic images were seen.

conclusionsThe application of a 16-gauge needle as an introducer showed improved efficacy in terms of the number of needle passes/attempts, first pass/attempt success rates, and procedural time in real-time ultrasound-guided subarachnoid anesthesia.

trial registrationThe study was registered in the Chinese Clinical Trial Registry (registration date February 27, 2023 registration number ChiCTR2300068702).

Indexed as

Anesthesia, ObstetricalAnesthesia, SpinalNeedlesUltrasonography, InterventionalAdultCesarean SectionFemaleHumansPregnancySubarachnoid SpaceAnesthetic techniquesParamedian transverse approachSpinal anesthesiaSubarachnoidUltrasonography

Identifiers

PMID41981398
PMCPMC13191935

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.