Evidence map›Paper›PMID 41981394›Full record

ArticleBMC pregnancy and childbirth2026

Association between maternal personality traits and fetal atherogenic indices: a cross-sectional study.

Leyla Haghighi Kaffash, Mohammad Miri, Hafez Heydari-Zarnagh, Mojgan Agahheris

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Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Leyla Haghighi KaffashDepartment of Health Psychology, Psychology Department, Payame Noor University, Tehran, Iran.
Mohammad MiriNon-communicable Diseases Research Center, Department of Environmental Health, School of Health, Sabzevar University of Medical Sciences, Sabzevar, Iran. M_miri87@yahoo.com.
Hafez Heydari-ZarnaghDepartment of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mojgan AgahherisDepartment of Health Psychology, Psychology Department, Payame Noor University, Tehran, Iran. agah.mojgan@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPersonality traits have been linked to an increased risk of cardiovascular diseases in adults through the development of atherogenic dyslipidemia. However, the potential influence of maternal personality traits on fetal atherogenic indices remains unexplored. This study aimed to determine the association between maternal personality traits and atherogenic indices in cord blood.

methodsIn this cross-sectional study, 384 mother-newborn pairs were enrolled. Triglyceride (TG), total cholesterol (TC), and high-density lipoprotein cholesterol (HDL-C) levels were measured in cord plasma. Low-density lipoprotein cholesterol (LDL-C) and non-HDL-C were calculated using TG, TC and HDL-C levels. Fetal atherogenic indices including TG/HDL-C, TG/LDL-C, TC/HDL-C, LDL-C/HDL-C and non-HDL-C/HDL-C ratios, were computed. Maternal personality traits were assessed using the NEO Five-Factor Inventory (NEO-FFI) questionnaire. The association between maternal personality traits and fetal atherogenic indices was examined using linear regression models.

resultsNostatistically significant associations were observed between maternal personality traits and fetal levels of TG, TC, LDL-C, HDL-C and non-HDL-C. Additionally, no significant associations were found between maternal personality traits and any of the fetal atherogenic indices (all p > 0.05).

conclusionTheresults indicate that maternal personality traits are not associated with atherogenic indices in fetal cord blood.

Indexed as

AtherosclerosisFetal BloodMothersPersonalityAdultCholesterolCholesterol, HDLCholesterol, LDLCross-Sectional StudiesFemaleHumansPregnancyTriglyceridesCholesterolCholesterol, HDLCholesterol, LDLTriglyceridesAtherogenic dyslipidemiaCholesterolFetal programmingLipidsPersonality

Identifiers

PMID41981394
PMCPMC13192107

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