Trial reportClinical oral investigations2026
Evaluation of orthodontically induced inflammatory root resorption (OIIRR) in adolescent patients with class II malocclusion undergoing treatment with rigid and hybrid fixed functional appliances: a randomized clinical trial.
Trial report in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo compare volumetric and linear root resorption in mandibular anterior teeth and maxillary first molars following treatment with rigid (Mandibular Protraction Appliance IV, MPA IV) and hybrid (Forsus Fatigue Resistant Device, Forsus FRD) fixed functional appliances, utilizing cone beam computed tomography (CBCT).
methodsThis prospective clinical trial included 32 patients with Skeletal Class II malocclusion (mean age, 15.71±2.62 years), randomized and allocated into two groups: Group 1 (n=16) treated with an MPA IV appliance, and Group 2 (n=16) treated with a Forsus FRD hybrid appliance. CBCT scans were acquired before treatment (T0) and after mandibular advancement with fixed functional appliance (T1). Volumetric measurements were calculated from the cementoenamel junction (CEJ) to the apex for mandibular anterior teeth and from the furcation area to the apex for maxillary first molars. Statistical analysis was performed using paired and unpaired t-tests with significance set at p<0.05.
resultsBoth appliances produced statistically significant volumetric and linear root resorption in all evaluated teeth (p<0.05). MPA IV group showed a mean volume reduction of 22.15 ± 8.0 mm³ in mandibular canines compared with 14.15 ± 4.23 mm³ in the Forsus group (p=0.001). Similarly, maxillary palatal root showed significantly more root resorption in MPA IV group (18.7 ± 8.52 mm³) as compared to Forsus FRD group (8.92 ± 4.3 mm³). A similar resorption pattern was also observed in the mandibular anterior region, with greater root resorption (both volumetric and linear) in MPA IV group compared with Forsus FRD group.
conclusionsBoth rigid (MPA IV) and hybrid (Forsus FRD) fixed functional mandibular advancement appliances cause statistically significant root resorption. However, the MPA IV appliance demonstrated greater volumetric root resorption in maxillary first molar palatal roots and mandibular canines.
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