Evidence map›Paper›PMID 41981121›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Prematurity and autism: a dose-response relationship across gestational age.

Ariel Israel, Francis B Mimouni, Shlomo Vinker, Joseph Mendlovic

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ariel IsraelLeumit Research Institute and Department of Pediatrics, Leumit Health Services, Tel Aviv, Israel. arielisrael@tauex.tau.ac.il.ORCID http://orcid.org/0000-0003-4389-8896
Francis B MimouniLeumit Research Institute and Department of Pediatrics, Leumit Health Services, Tel Aviv, Israel.
Shlomo VinkerLeumit Research Institute and Department of Pediatrics, Leumit Health Services, Tel Aviv, Israel.
Joseph MendlovicMinistry of Health, Jerusalem, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo characterize how autism spectrum disorder (ASD) risk varies with gestational age at birth. STUDY

designWe conducted a retrospective cohort study of children born between 2011 and 2023. ASD was identified using ICD-10 codes. Each ASD case (n = 1861) was matched to ten controls using exact and propensity-score matching on sex, birth year, maternal age, ethnic sector, socioeconomic status, and region. Gestational age was grouped into clinically relevant categories, and associations with ASD were evaluated using Fisher's exact test and conditional logistic regression.

resultsASD risk increased progressively with prematurity. Compared with term birth (37-42 weeks), adjusted odds ratios (95% CI) were 1.37 (1.10-1.71) at 36 weeks, 1.67 (1.30-2.15) at 34-35 weeks, 2.14 (1.43-3.18) at 32-33 weeks, 2.95 (1.89-4.59) at 28-31 weeks, and 4.37 (2.26-8.44) below 28 weeks.

conclusionEarlier gestational age is associated with increased ASD risk in a dose-response manner.

Identifiers

PMID41981121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.