Evidence map›Paper›PMID 41981050›Full record

ArticleScientific reports2026

A cut-off value for endothelial dysfunction based on the triglyceride-glucose index.

Takayuki Yamaji, Farina Mohamad Yusoff, Shinji Kishimoto, Masato Kajikawa, Takahiro Harada, Aya Mizobuchi, Shunsuke Tanigawa, Tatsuya Maruhashi, Yukiko Nakano, Yukihito Higashi

Abstract read
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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Takayuki YamajiCenter for Radiation Disaster Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Farina Mohamad YusoffDepartment of Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.
Shinji KishimotoDepartment of Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.
Masato KajikawaDivision of Regeneration and Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan.
Takahiro HaradaDepartment of Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.
Aya MizobuchiDepartment of Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.
Shunsuke TanigawaDepartment of Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.
Tatsuya MaruhashiDepartment of Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.
Yukiko NakanoDepartment of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan.
Yukihito HigashiCenter for Radiation Disaster Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan. yhigashi@hiroshima-u.ac.jp.

Funding

Japan Society for the Promotion of Science 18590815Japan Society for the Promotion of Science 24K19059
6 · The paper itself

Abstract

We defined triglyceride-glucose (TyG) index < 8.52 as a low TyG index and TyG index ≥ 8.52 as a high TyG index, and divided the subjects into nine groups based on the levels of TyG index and fasting blood glucose (FBG) levels: FBG levels < 90 mg/dL and low TyG index, FBG levels < 90 mg/dL and high TyG index, FBG levels of 90-94 mg/dL and low TyG index, FBG levels of 90-94 mg/dL and high TyG index, FBG levels of 95-99 mg/dL and low TyG index, FBG levels of 95-99 mg/dL and high TyG index, FBG levels of 100-125 mg/dL and low TyG index, FBG levels of 100-125 mg/dL and high TyG index, and diabetes mellitus. The odds ratios for endothelial dysfunction were significantly higher in groups with high TyG index and any levels of FBG, and the group with low TyG index and FBG levels of 95-99 mg/dL, the group with low TyG index and FBG levels of 100-125 mg/dL and the diabetes mellitus group than the FBG levels < 90 mg/dL and low TyG index group. Even at a low TyG index, subjects with FBG levels ≥ 95 mg/dL might have a higher risk for endothelial dysfunction.

Indexed as

Blood GlucoseEndothelium, VascularTriglyceridesFemaleHumansMaleBlood GlucoseTriglycerides

Identifiers

PMID41981050
PMCPMC13234090

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.