Evidence map›Paper›PMID 41980979›Full record

ArticleNature communications2026

Medullary cavity expansion is mediated by distinct cell populations during fetal bone development.

Eriko Sumiya, Kohei Saeki, Kenta Nakano, Chie Kikutake, Noriko Kurisaki, Natsuko Nakaima, Mami Kurumata-Shigeto, Yumiko Kitada, Yuka Morioka, Yasuhiro Go and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Eriko SumiyaDivision of Mucosal Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0009-0005-7086-3287
Kohei SaekiDepartment of Veterinary Medicine, Okayama University of Science, Imabari, Japan.
Kenta NakanoDepartment of Laboratory Animal Medicine, National Institute of Global Health and Medicine, Japan Institute for Health Security (JIHS), Tokyo, Japan.ORCID http://orcid.org/0000-0003-2617-1468
Chie KikutakeDivision of Bioinformatics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Noriko KurisakiDivision of Mucosal Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Natsuko NakaimaDepartment of Skeletal Development and Regenerative Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Mami Kurumata-ShigetoDivision of Mucosal Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Yumiko KitadaDivision of Mucosal Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Yuka MoriokaDivision of Disease Model Innovation, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.
Yasuhiro GoCognitive Genomics Research Group, Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, Okazaki, Japan.ORCID http://orcid.org/0000-0003-4581-0325
Mikita SuyamaDivision of Bioinformatics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0001-9526-3193
Yuki YoshimuraCentral Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, Japan.ORCID http://orcid.org/0000-0001-7092-6683
Motohito GotoCentral Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, Japan.ORCID http://orcid.org/0000-0001-6288-4583
Mamoru ItoCentral Institute for Experimental Medicine and Life Science (CIEM), Kawasaki, Japan.ORCID http://orcid.org/0000-0002-5373-8223
Manabu NakayamaLaboratory of Medical Omics Research, Department of Frontier Research and Development, Kazusa DNA Research Institute, Kisarazu, Japan.ORCID http://orcid.org/0009-0001-0488-1664
Haruhiko AkiyamaDepartment of Orthopedic Surgery, School of Medicine, Gifu University, Gifu, Japan.
Lucie PedutoStroma, Inflammation & Tissue Repaire Unit, Institut Pasteur, Paris, 75015, France.ORCID http://orcid.org/0000-0003-2414-4407
Tadashi OkamuraDepartment of Laboratory Animal Medicine, National Institute of Global Health and Medicine, Japan Institute for Health Security (JIHS), Tokyo, Japan.ORCID http://orcid.org/0000-0001-8457-1561
Yuki MatsushitaDepartment of Skeletal Development and Regenerative Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.ORCID http://orcid.org/0000-0001-9577-3249
Shinichiro SawaDivision of Mucosal Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan. sawa.shinichiro.353@m.kyushu-u.ac.jp.ORCID http://orcid.org/0000-0002-8850-446X

Funding

Japan Agency for Medical Research and Development (AMED) JP19gm6310005,MEXT | Japan Society for the Promotion of Science (JSPS) 17K15588MEXT | Japan Society for the Promotion of Science (JSPS) 21K08417MEXT | Japan Society for the Promotion of Science (JSPS) 25K22772MEXT | Japan Society for the Promotion of Science (JSPS) JP22J40144MEXT | Japan Society for the Promotion of Science (JSPS) JP23K27428
6 · The paper itself

Abstract

Bone marrow (BM) is the primary site of postnatal hematopoiesis, yet how it is established during embryogenesis remains poorly understood. BM formation is initiated by the invasion of vascular and mesenchymal cells into a preformed cartilage template, generating the primary ossification center (POC). Here, we identify CD55

Indexed as

Bone DevelopmentAnimalsBone MarrowFemaleHematopoiesisMesenchymal Stem CellsMiceMice, Inbred C57BLOsteoclastsOsteogenesis

Identifiers

PMID41980979
PMCPMC13254312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.