Evidence map›Paper›PMID 41980860›Full record

ArticleThe Laryngoscope2026

Micro-CT Evaluation of Robot-Assisted Insertion of CI632 Implant in Human Cadaveric Temporal Bones.

Sean C Sheppard, Hannah Daoudi, Resul Ekici, Daniele De Seta, Evelyne Ferrary, Isabelle Mosnier, Ghizlene Lahlou, Thierry Van Den Abbeele, Renato Torres, Yann Nguyen

Abstract read
In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sean C SheppardUniversité Paris Cité, Institut Pasteur, AP-HP, Inserm, CNRS, Fondation Pour l'Audition, IHU reConnect, Technologies et thérapie génique pour la surdité, Paris, France.ORCID https://orcid.org/0000-0001-6427-3102
Hannah DaoudiUniversité Paris Cité, Institut Pasteur, AP-HP, Inserm, CNRS, Fondation Pour l'Audition, IHU reConnect, Technologies et thérapie génique pour la surdité, Paris, France.
Resul EkiciCollin, Bagneux, France.
Daniele De SetaDepartment of Sense Organs, ENT Department, Sapienza University of Rome, Rome, Italy.
Evelyne FerraryUniversité Paris Cité, Institut Pasteur, AP-HP, Inserm, CNRS, Fondation Pour l'Audition, IHU reConnect, Technologies et thérapie génique pour la surdité, Paris, France.
Isabelle MosnierUniversité Paris Cité, Institut Pasteur, AP-HP, Inserm, CNRS, Fondation Pour l'Audition, IHU reConnect, Technologies et thérapie génique pour la surdité, Paris, France.
Ghizlene LahlouUniversité Paris Cité, Institut Pasteur, AP-HP, Inserm, CNRS, Fondation Pour l'Audition, IHU reConnect, Technologies et thérapie génique pour la surdité, Paris, France.ORCID https://orcid.org/0000-0002-1067-045X
Thierry Van Den AbbeeleAP-HP/Université Paris Cité, Hôpital Robert Debré, Service de Chirurgie ORL et cervico-faciale pédiatrique, Inserm NeuroDiderot, Paris, France.
Renato TorresUniversité Paris Cité, Institut Pasteur, AP-HP, Inserm, CNRS, Fondation Pour l'Audition, IHU reConnect, Technologies et thérapie génique pour la surdité, Paris, France.
Yann NguyenUniversité Paris Cité, Institut Pasteur, AP-HP, Inserm, CNRS, Fondation Pour l'Audition, IHU reConnect, Technologies et thérapie génique pour la surdité, Paris, France.

Funding

Agence Nationale de la Recherche ANR-23-IAHU-0003Fondation Pour l'Audition FPA IDA08Fondation Pour l'Audition FPA RD-2022-09Gottfried & Julia Bangerter-Rhyner FoundationInstitut Pasteur
6 · The paper itself

Abstract

objectiveTo evaluate the surgical accuracy and intracochlear positioning of robot-assisted insertion of slim modiolar cochlear implant electrode arrays (CI632) using the RobOtol system in human cadaveric temporal bones.

methodsA total of 14 fresh-frozen adult cadaveric temporal bones underwent cochlear implantation using RobOtol robot-assistance. Standard mastoidectomy, posterior tympanotomy, and round window exposure were performed. CI632 electrode arrays were robotically inserted at a speed of 0.1 mm/s. Postoperative micro-computed tomography (micro-CT) was performed to assess electrode scalar position, angular insertion depth, modiolar proximity (intracochlear position index), and frequency-to-place mismatch.

resultsRobot-assisted insertion of all 22 electrodes was successfully achieved in 14 specimens. Micro-CT analysis confirmed scala tympani placement without evidence of translocation. A total of 13 arrays demonstrated correct perimodiolar positioning, while one was misplaced along the lateral wall. Mean insertion angle of the 13 correctly placed arrays was 406° ± 25° (351°-441°), and mean intracochlear position index was 0.5 ± 0.05. One array (7%) was mispositioned with lateral wall placement, which occurred in a cochlea with a large cochlear duct length (36.4 mm) and a wide basal turn at 90° (4.6 mm). Frequency-to-place mismatch varied across specimens, with a mismatch of 2637 ± 663 Hz (1973-4077 Hz) for the 8th electrode, and 1246 ± 317 Hz (899-1948 Hz) for the 16th electrode, corresponding to approximately one octave.

conclusionRobot-assisted insertion of slim modiolar electrode arrays was feasible and reproducible in human cadaveric temporal bones. One case of mispositioned array occurred in a cochlea with large dimensions, underscoring the importance of preoperative anatomical assessment. LEVEL OF EVIDENCE: N/A.

Indexed as

Cochlear ImplantationCochlear ImplantsRoboticsRobotic Surgical ProceduresTemporal BoneX-Ray MicrotomographyCadaverElectrodes, ImplantedHumanscochlear implantfrequency‐to‐place mismatchinsertion traumaprofound hearing lossslim modiolar electrode array

Identifiers

PMID41980860
PMCPMC13460615

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.